472 Crystallization of Pharmaceutical and Biological Molecules


Description:
This session welcomes papers addressing fundamental as well as applied studies in the area of crystallization of pharmaceutical or biological molecules. Topics related to experimental studies, theory and simulation that contribute to fundamental understanding of crystallization as well as industrial case studies on the crystallization development of pharmaceutical and biological compounds are encouraged.

Sponsor:
Crystallization and Evaporation
Co-Sponsor(s):
Pharmaceuticals (15B), Pharmaceutical Discovery, Development and Manufacturing Forum (26)


Chair:
Ryan C. Snyder
Assistant Professor of Chemical Engineering
Bucknell University
Chemical Engineering
701 Moore Ave, Box A0551
Lewisburg, PA
17837
Email: rcs048@bucknell.edu

Co-chairs:
Venkateswarlu Bhamidi
Eastman Chemical Company
Kingsport, TN
37660
Email: vbhamidi@eastman.com

Ying Diao
Assistant Professor and Dow Chemical Company Faculty Scholar
University of Illinois at Urbana Champaign
Chemical and Biomolecular Engineering
Urbana, IL
Phone Number: 2173003505
Email: yingdiao@illinois.edu


Papers:
Introductory Remarks
472a
Pinducer Analysis for the Design of a Nucleation Subsystem for Continuous Slug-Flow Crystallization
Mo Jiang, Massachusetts Institute of Technology; Chen Gu, Massachusetts Institute of Technology; Richard D. Braatz, Massachusetts Institute of Technology
472b
Understanding Metastable Zone Width without Nucleation Rate
Venkateswarlu Bhamidi, Eastman Chemical Company; Paul J. A. Kenis, University of Illinois at Urbana-Champaign; Charles F. Zukoski, University at Buffalo
472c
Molecular Interactions between Nanocellulose and Crystallizing Pharmaceuticals
Manali Banerjee, Georgia Institute of Technology; Blair Kathryn Brettmann, Georgia Institute of Technology
472d
A New Model for Solubility Prediction to Guide Solvent Selection for Process Development
Michael Lovette, Amgen Inc.
472e
Heterogeneous Nucleation of Small Molecule Crystals in the Presence of Nanoparticles
Lucrèce Nicoud, Massachusetts Institute of Technology; Leia Dwyer, Massachusetts Institute of Technology; Allan S. Myerson, Massachusetts Institute of Technology
472f
The Influence of Solution Conditions on the Self-Assembly of Pre-Nucleation Clusters
Eftychios Hadjittofis, Imperial College London; Mark A. Isbell, imperial college london; Geoff G. Z. Zhang, AbbVie Inc.; Jerry Heng, Imperial College London
472g
Simulations and Experiments Validation on the Membrane Based Response Technology for Nucleation Detection and Crystallization Control
Xiaobin Jiang, Dalian University of Technology; Wu Xiao, Dalian University of Technology; Dapeng Lu, Dalian University of Technology; Rui Zhao, Dalian University of Technology; Gaohong He, Dalian University of Technology
Concluding Remarks
Abstract Submissions Closed
See more of this Group/Topical: Separations Division
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