443 Particle Engineering and Design for Product Value Enhancement


Description:
This session seeks papers whose scope is within the broadly defined area of Particle Engineering as applied in various industries such as pharmaceuticals, food, agrochemicals, cosmetics, etc. Various active agents or key functional ingredients are designed into particulate products in such a way to achieve controllable, reproducible, and effective functional responses in terms of product performance. These functional responses greatly depend on the dosage form and the way active agents and inert/excipient particles are integrated into the superstructure of the product. Particle engineering offers tools and methodologies, both experimental and numerical, to design the structure of particles so that the desired responses of the active agents are enhanced significantly in the dosage form. Particles and their surfaces can be designed and tailored in many different processes via different formulation approaches. Both novel formulations and the manufacturing processes that yield engineered particles are of interest to this session, as well as scientific approaches that relate particle formation, structure and functional performance. Papers can be experimental in nature, while fundamental theoretical or modeling works (e.g. based on DEM, FEM, CFD, or any combination in a multi-scale fashion) providing insight into the formation and behavior of the particles in the dosage form are also welcome.

Sponsor:
Particle Production and Characterization


Chair:
Ecevit Bilgili
Associate Professor
New Jersey Institute of Technology
Otto H. York Department of Chemical, Biological, and Pharmaceutical Engineering
161 Warren St. 150 Tiernan Hall
Newark, NJ
07102
Phone Number: 973-596-2998
Email: bilgece@njit.edu

Co-Chair:
Ilgaz Akseli
Director
Celgene
R&D Pharmaceutical Development
900 Ridgebury Rd
Summit, NJ
06877
Email: iakseli@celgene.com


Papers:
Dry Mechanical Processing for Value-Enhanced Excipients
Liang Chen, New Jersey Institute of Technology; Xiaoyi Ding, New Jersey Institute of Technology; Siqi Fan, New Jersey Institute of Technology; Rajesh Davé, New Jersey Institute of Technology
Assessing the Impact of Dry Coating on the Surface Properties of Pharmaceutical Formulations
Eftychios Hadjittofis, Imperial College London; Geoff G. Z. Zhang, AbbVie Inc.; Jerry Heng, Imperial College London
Critical Material Attributes (CMAs) of Strip Films Loaded with Poorly Water-Soluble Drug Particles: IV. Surface-Modified Dry Micronized Drug Powders
Lu Zhang, New Jersey Institute of Technology; Yidong Li, New Jersey Institute of Technology; Abed Manal, New Jersey Institute of Technology; Rajesh Davé, New Jersey Institute of Technology
Synthesis and Stability Study of Polymorphic Transformed Mannitol/ LB Agar Microcarriers for Dry Powder Inhalation
Fengying Zhang, Nanyang Technological University; Thi Quynh Ngoc Nguyen, Nanyang Technological University; Raymond Lau, Nanyang Technological University
Understanding the Surface Chemistry, Surface Roughness and Wettability of Argon Plasma Treated Cornstarch Powder
Deepa Dixit, Indian Institute of Technology Gandhinagar; Shreya Bunk, Indian Institute of Technology Kharagpur; Ramkrishna Rane, Institute for Plasma Research; Chinmay Ghoroi, Indian Institute of Technology Gandhinagar
Effects of Baffle Configuration and Tank Size on Spherical Agglomerates of Dimethyl Fumarate in a Common Stirred Tank
Tu Lee, National Central University; Po-Yen Lin, National Central University; Hung-Lin Lee, National Central University; Chih-Wei Chen, National Central University
Using Magnetically Assisted Impact Coating (MAIC) for Optimization of Powder Flow Characteristics
Charles R. Bowman, AVEKA Inc; Tim Freeman, Freeman Technology Ltd; William A. Hendrickson, AVEKA Inc; Christopher J. Rueb, AVEKA Inc; Robert G. Bowman, AVEKA Inc; Katrina Brockbank, Freeman Technology Ltd; Jamie Clayton, Freeman Technology Ltd; Christine M. Colby, AVEKA Inc
Abstract Submissions Closed
See more of this Group/Topical: Particle Technology Forum