26 Green Pharmaceutical Process Development and Biocatalysis


Description:
The session illustrates status and progress in the design of processes for pharmaceuticals that incorporate the concepts of Green Chemistry or of biocatalysis. Thus, contributions are highly encouraged to include Green Chemistry concepts and results, especially those that are backed up with quantitative metrics, or to include one or more biocatalytic steps.

Sponsor:
Pharmaceutical Discovery, Development and Manufacturing Forum
Co-Sponsor(s):
Pharmaceuticals (15B)


Chair:
Andreas S. Bommarius
Professor
Georgia Institute of Technology
School of Chemical & Biomolecular Engineering
Parker H. Petit Institute for Bioengineering and Bioscience
Atlanta, GA
30332
Fax Number: 404-894-2291
Email: andreas.bommarius@chbe.gatech.edu

Co-Chair:
Shane T. Grosser
Senior Chemical Engineer
Merck & Co., Inc.
Chemical Process Development and Commercialization
126 E. Lincoln Ave.
Rahway, NJ
07065
Fax Number: 732-594-7355
Email: shane_grosser@merck.com


Papers:
26a
Developing Improved Enzymes for Industrial Biocatalysis
Iman Farasat, Merck
26b
Technoeconomic Optimisation, Antisolvent Selection and Comparative Environmental Evaluation for Continuous Paracetamol Crystallisation
Hikaru G. Jolliffe, University of Edinburgh; Dimitrios I. Gerogiorgis, University of Edinburgh
26c
Metric-Driven Process Development of a Late Stage Drug Substance
Kathleen Lauser, Bristol-Myers Squibb Co.; Nathan Domagalski, Bristol-Myers Squibb; Michaël Fenster, Bristol-Myers Squibb Company; Thomas La Cruz, Bristol Myers Squibb Co; Max A. Mellmer, Bristol-Myers Squibb Co; Eric M. Saurer, Bristol-Myers Squibb Co.; Matthew Winston, Bristol Myers Squibb Co.
26d
Scalable Continuous Synthesis of Enantiomerically Pure Amine APIs in an Enzyme Membrane Reactor
Robert D. Franklin, Georgia Institute of Technology; Bettina Bommarius, Georgia Institute of Technology; Andreas S. Bommarius, Georgia Institute of Technology
26e
Development of a Biocatalytic Cascade for the Deracimization of a Racemic Alcohol
Shane T. Grosser, Merck & Co., Inc.
26f
Design of New Reactors to Produce Levan Biopolymer through Enzymatic Catalysis: Kinetics and Mass Transfer
Álvaro González-Garcinuño, University of Salamanca; Alvaro Sanchez, University of Salamanca; Sonia Ruiz, University of Salamanca; Antonio Tabernero, University of Salamanca; Miguel A. Galan, University of Salamanca; Montaña Elviro, University of Salamanca; Antonio Monzón, University of Zaragoza; Eva Martín del Valle, University of Salamanca
Abstract Submissions Closed
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