67 Emerging Tools and Enabling Technologies in Synthetic Biology and Metabolic Engineering


Description:
Synthetic biology applies engineering principles to construct biological systems with unique and useful properties. The process of design and construction of these systems poses major challenges, owing to the complexity of biology. However, emerging tools have enabled the rapid construction of increasingly complex systems with predictable behaviors. This session will cover the development and application of these tools to the diverse topics of synthetic biology. Topics include, but are not limited to, DNA assembly, genetic circuit design and validation, modeling approaches, biomolecular breadboarding, synthetic regulation, cell-cell communication, RNA-based control schemes, and general understanding of biology that stems from design and construction of synthetic systems. Systems will span from in vitro experiments, viruses, and diverse bacteria to eukaryotes (yeast, mammalian cells, and plants). This session will focus particularly on the development of synthetic biology technology and approaches.

Sponsor:
Bioengineering


Chair:
Kang Wu
Assistant Professor
University of New Hampshire
Chemical Engineering
Durham, NH
Email: kang.wu@unh.edu

Co-Chair:
Cong T. Trinh
Assistant Professor
University of Tennessee
Department of Chemical and Biomolecular Engineering
Knoxville, TN 37996
Knoxville, TN
37996
Email: ctrinh@utk.edu


Papers:
67a
Modifying IgG Glycan Profile Using a High-Throughput Multi-Gene Assembly Platform
Christopher Stach, University of Minnesota, Twin Cities; Tung S. Le, University of Minnesota, Twin Cities; Meghan G. McCann, University of Minnesota, Twin Cities; Xinning Chen, East China University of Science & Technology; Liang Zhao, East China University of Science & Technology; Michael J. Smanski, University of Minnesota, Twin Cities; Wei-Shou Hu, University of Minnesota, Twin Cities
67b
Synthetic Regulation of Sporulation Genes for Tunable Display of Proteins on Bacterial Spore Surface
Jiacheng Wan, University of New Hampshire; Erin Drufva, University of New Hampshire; Kang Wu, University of New Hampshire
67e
Kinetically-Controlled RNA Aptamer Biosensors for High-Throughput Production Phenotype Screening
Cassandra Burke, University of Washington; James Carothers, University of Washington
67c
Modcell: A Multiobjective Strain Design Platform for Modular Cell Engineering
Sergio Garcia, University of Tennessee; Cong T. Trinh, University of Tennessee
67f
Optimization Driven Top-Down Synthesis of Genome Minimized Strains for Bioproduction
Lin Wang, The Pennsylvania State University; Costas D. Maranas, The Pennsylvania State University
67g
Genome-Scale Engineering: A New Frontier in Metabolic Engineering
Huimin Zhao, University of Illinois at Urbana-Champaign
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division