692 Advances in Biocatalysis and Biosynthesis II: Enzyme Engineering Applications


Description:
This session focuses on the development of new techniques in biocatalysis and biosynthesis of small molecules, including fine chemicals and natural products. Suggested topics include, but are not limited to: (1) Discovery, characterization, and engineering of enzyme reactions and biosynthetic pathways; (2) Rational and combinatorial manipulation of biosynthetic pathways; and (3) Development of activity screening methods and assays. Topics that cover the metabolic engineering of primary metabolites are better suited in the metabolic engineering sections.

Sponsor:
Bioengineering


Chair:
Bradley C. Bundy
Associate Professor
Brigham Young University
Chemical Engineering
350S Clyde Building
Provo, UT
84602
Email: bundy@byu.edu

Co-Chair:
Robert Jinkerson
Fellow
Carnegie Institution, Stanford University
260 Panama Street
Stanford, CA
94305
Email: rjinkerson@carnegiescience.edu


Papers:
692a
A Versatile Synthetic Biology Platform for High-Throughput Structure and Activity Screening of Ribosomally-Synthesized and Post-Translational Modified Peptides (RiPPs)
Tong Si, University of Illinois at Urbana-Champaign; Jonathan V. Sweedler, University of Illinois at Urbana-Champaign; Wilfred A. van der Donk, University of Illinois at Urbana-Champaign; Huimin Zhao, University of Illinois at Urbana-Champaign
692b
Hydroclassified Combinatorial Saturation Mutagenesis for Evolving Stereoselectivity and Cosubstrate Specificity of a Diaryl Alcohol Dehydrogenase
Ye Ni, Jiangnan University; Jieyu Zhou, Jiangnan University; Guochao Xu, Jiangnan University
692c
Facilitating Electron Channeling in a Self-Assembling Metabolon Containing Two Dehydrogenases and a Nife-Hydrogenase
Hui Chen, Virginia Tech; Y.-H. Percival Zhang, Virginia Polytechnic Institute and State University
692d
Beyond Iron: Iridium-Containing P450 for Selective Cyclopropanations of Alkenes
Hanna Key, University of California Berkeley; Pawel Dydio, University of California Berkeley; Zhennan Liu, University of California Berkeley; Douglas S. Clark, University of California; John F. Hartwig, UCB
692e
Bioprospecting to Discover Keto-Aryl Reductases with Enhanced Specificity Towards Longer-Chain, Aliphatic Substrates
Jason T. Boock, Massachusetts Institute of Technology; Yekaterina Tarasova, MIT; Kristala L.J. Prather, Massachusetts Institute of Technology
692f
Microbial Synthesis of Novel Terpenoid-Based Inhibitors
Edward Y. Kim, University of Colorado, Boulder; Jerome M. Fox, University of Colorado, Boulder
692g
Extreme Makeover: Engineering the Thermostable Alcohol Dehydrogenase D (AdhD) Protein Scaffold for New Applications
Scott Banta, Columbia University
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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