526637 Green Process Development and Characterization of an Alkylation Reaction to Improve API Impurity Control

Cuixian Yang1, Michael Ward1, Guy Humprey2, Bharath Krishnamurthi1, Erik Dienemann1, Timothy Wright1, Nicholas Rogus3, Anne Mohan1 and Peter Maligres2, (1)Chemical Engineering Research and Development, Merck & Co., Inc., Rahway, NJ, (2)Process Chemistry & Enabling Technology, Merck & Co., Inc., Rahway, NJ, (3)Process R&D, Merck & Co. Inc., Rahway, NJ
See more of this Session: Developing Process Control Strategies for Drug Substance Manufacture
See more of this Group/Topical: Pharmaceutical Discovery, Development and Manufacturing Forum