Hengqian Ren1, Subhanip Biswas2, Sherri Ho2, Wilfred A. van der Donk3 and Huimin Zhao4, (1)Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, (2)University of Illinois at Urbana-Champaign, Urbana, IL, (3)Howard Hughes Medical Institute, University of Illinois at Urbana-Champaign, Urbana, IL, (4)Department of Chemical and Biomolecular Engineering, Department of Chemistry and Biochemistry, Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL