Fan Zhang1, Michael Coon1, Sirkka Stephan1, Smitha Pillai2 and Matthias Stephan1,3,4,5, (1)Clinical Research Devision, Fred Hutchinson Cancer Research Institute, Seattle, WA, (2)Comparative Pathology, Fred Hutchinson Cancer Research Institute, Seattle, WA, (3)Technology Access Foundation (TAF) Academy, Fred Hutchinson Cancer Research Institute, Seattle, WA, (4)Bioengineering and Molecular Engineering and Sciences Institute, University of Washington, Seattle, WA, (5)Department of Medicine, Division of Medical Oncology, University of Washington, Seattle, WA