534959 Defining the Optimal Operating Window for Pharmaceutical Reactions Using the Dynamic Response Surface Methodology for All Measured Species

Yachao Dong1, Christos Georgakis1, Jason Mustakis2, Joel M. Hawkins2, Jonathan P. McMullen3 and Shane T. Grosser4, (1)Systems Research Institute and Chemical and Biological Engineering, Tufts University, Medford, MA, (2)Pfizer Global Research & Development, Pfizer Inc., Groton, CT, (3)Process R&D, Merck & Co. Inc., Rahway, NJ, (4)Chemical Engineering R&D, Merck & Co., Inc., Rahway, NJ
See more of this Session: Multivariate Experimentation and Modeling for Pharmaceutical Products and Processes
See more of this Group/Topical: Pharmaceutical Discovery, Development and Manufacturing Forum