535200 A Constrained Version of the Dynamic Response Surface Methodology for Challenging Time-Resolved Pharmaceutical Reaction Data

Yachao Dong1, Christos Georgakis1, Jason Mustakis2, Joel M. Hawkins2, Lu Han2, Jonathan P. McMullen3 and Shane T. Grosser4, (1)Systems Research Institute and Chemical and Biological Engineering, Tufts University, Medford, MA, (2)Pfizer Global Research & Development, Pfizer Inc., Groton, CT, (3)Process R&D, Merck & Co. Inc., Rahway, NJ, (4)Chemical Engineering R&D, Merck & Co., Inc., Rahway, NJ
See more of this Session: Innovations in Pharmaceutical Discovery, Development, and Manufacturing
See more of this Group/Topical: Pharmaceutical Discovery, Development and Manufacturing Forum