535300 Characterizing Protein-Protein Interactions in Highly Concentrated Monoclonal Antibody Solutions Using Small Angle X-Ray Scattering and Molecular Dynamics Simulations

Amjad Chowdhury1, Barton J. Dear1, Jonathan A. Bollinger2, Jessica Hung1, P. Douglas Godfrin3, Maria P. Nieto1, Tony Shay1, Logan Wilks1, Carl Karouta1, Thomas M. Truskett4 and Keith P. Johnston1, (1)McKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, (2)Center for Integrated Nanotechnologies, Sandia National Laboratories, Albuquerque, NM, (3)Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, (4)Chemical Engineering and Institute for Theoretical Chemistry, The University of Texas at Austin, Austin, TX