535894 A Modeling Framework to Characterize Kinetics, Efficacy and Toxicity of Hydroxyurea Based Treatment of Individual Sickle Cell Disease Patients

Akancha Pandey1, Robert Hannemann1,2, Peter Kissinger3, Seethal Jacob4, Terry Vik4, Sangtae Kim1 and Doraiswami Ramkrishna1, (1)Davidson School of Chemical Engineering, Purdue University, West Lafayette, IN, (2)Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, (3)Department of Chemistry, Purdue University, West Lafayette, IN, (4)Indiana University Health, Indianapolis, IN