426 Thermodynamics of Biomolecular Folding and Assembly


Description:
Biological systems require precise folding, recognition, and self-assembly behaviors to form complex nanostructures and molecular machines. This session solicits theoretical, computational, and experimental studies that address aspects of both natural and synthetic biomolecule folding and assembly. We encourage submissions that focus on fundamental biophysical thermodynamic and transport properties, mechanisms, and models. Topics of interest include: protein, RNA, and DNA folding and stability; design of structure and function; biomolecules at interfaces and under confinement; and biomolecular self-assembly into materials and machines.

Sponsor:
Thermodynamics and Transport Properties


Chair:
Sapna Sarupria
Assistant Professor
Clemson University
Chemical and Biomolecular Engineering
Clemson, SC
29634
Email: ssarupr@g.clemson.edu

Co-Chair:
Reid Van Lehn
Assistant Professor
University of Wisconsin-Madison
Chemical and Biological Engineering
1200 E California Blvd
Madison, WI
91125
Email: vanlehn@wisc.edu


Papers:
Computational Investigation of the Effect of Backbone Chiral Inversions on Protein Folding
Gul H. Zerze, Princeton University; Frank H. Stillinger, Princeton University; Pablo Debenedetti, Princeton University
The Hydrophobicity and Conformations of Common Glycosylation Motifs across the Kingdoms of Life
Landon Mills, University of Kentucky; Gregg T. Beckham, National Renewable Energy Laboratory; Christina M. Payne, University of Kentucky
Simulation-Aided Design of Intrinsically Disordered Proteins with Tunable Phase Behavior
Gregory L. Dignon, Lehigh University; Jeetain Mittal, Lehigh University; Wenwei Zheng, Arizona State University
Towards a Thermodynamic Model for Predicting Coiled-Coil Protein Structures
Mojtaba Jokar, Wayne State University; Korosh Torabi, Wayne State University
Molecular Simulations of a Biomimetic Polymer in Protein Aggregation
Aviel Chaimovich, Science Consilience; Christian Leitold, University of California Santa Barbara; Christoph Dellago, University of Vienna, Faculty of Physics
Simulations and Experiments Delineate Amyloid Fibrilization By Peptides Derived from Glaucoma-Associated Myocilin
Yiming Wang, North Carolina State University; Yuan Gao, Georgia Institute of Technology; Shannon E. Hill, Georgia Institute of Technology; Dustin J. E. Huard, Georgia Institute of Technology; Moya O. Tomlin, Georgia Institute of Technology; Raquel L. Lieberman, Georgia Institute of Technology; Anant K. Paravastu, Georgia Institute of Technology; Carol K. Hall, North Carolina State University
Inferring Effects of Sequence on Structure of Anti-Microbial Peptides through Molecular Dynamics and Normal Mode Analysis
Faramarz Joodaki, University of Rhode Island; Lenore M. Martin, University of Rhode Island; Michael L. Greenfield, University of Rhode Island
Β-Wrapin Proteins Sequestering Amyloidogenic Proteins: Understanding Their Function and Designing Novel β-Wrapins with Improved Binding Affinities
Asuka A. Orr, Texas A&M University; Sai Vamshi R Jonnalagadda, Texas A&M University; Wolfgang Hoyer, Heinrich-Heine-Universitaẗ Düsseldorf; Phanourios Tamamis, Texas A&M University
Driving Towards Selection of Folded and Highly Structured Nucleic Acid Templates
Chiamaka Obianyor, Georgia Institute of Technology; Adriana Lozoya Colinas, Georgia Institute of Technology; Martha A. Grover, Georgia Institute of Technology; Nicholas Hud, Georgia Institute of Technology
Atomistic Simulation Studies of DNA-Porphyrin Nanoassemblies
Lev Levintov, University of New Hampshire; Harish Vashisth, UNIVERSITY OF NEW HAMPSHIRE
Abstract Submissions Closed
See more of this Group/Topical: Engineering Sciences and Fundamentals