314 Advancements in Materials Science for Powder Handling in Pharmaceutical Process Development


Description:
This session includes papers within the scope of particle engineering and material sciences of active pharmaceutical ingredients and excipients to enable pharmaceutical formulation design and development, specifically centered on powder handling processes. Abstracts related to novel process designs to achieve product specifications, methods to understand and manipulate particle attributes and scale up of particle engineering are of interest. Advancements in experimental, theoretical, and computational tools to characterize and predict solid properties are considered, as are particle engineering approaches for powder processing improvements.

Sponsor:
Pharmaceutical Discovery, Development and Manufacturing Forum
Co-Sponsor(s):
Pharmaceuticals (15B)


Chair:
Mohammad Azad
Postdoctoral Associate
Massachusetts Institute of Technology (MIT)
Chemical Engineering
Cambridge, MA
07102
Phone Number: 9733929769
Fax Number: 973-642-7088
Email: mazad@mit.edu

Co-chairs:
Anil Rane
Principal Scientist
Pfizer Gloabl Reseach and Development
CRD
Eastern point Rd
Groton, CT
06340
Email: anil.rane@pfizer.com

Athanas Koynov
Merck
Rahway, NJ
Email: Athanas.Koynov@merck.com


Papers:
314a
Round Granules of Dimethyl Fumarate By Three-in-One Intensified Process of Reaction, Crystallization, and Spherical Agglomeration in a Common Stirred Tank
Tu Lee, National Central University; Chih-Wei Chen, National Central University
314b
Systematic Approach to High Dosage Formulation Development for Continuous Direct Compression
Barbara Schaller, Bernal Institute, University of Limerick; Kevin Moroney, Bernal Institute, University of Limerick; Bernardo Castro Dominguez, University of Bath; Patrick Cronin, Bernal Institute, University of Limerick; Denise Croker, Bernal Institute, University of Limerick; Gavin Walker, Bernal Institute, University of Limerick
314c
Comparing High Drug Loaded Blend and Tablet Property Improvement Via Various Nano-Silica Dry Coating and Excipient Selection
Kuriakose Kunnath, New Jersey Institute of Technology; Zhonghui Huang, New Jersey Institute of Technology; Liang Chen, New Jersey Institute of Technology; Kai Zheng, New Jersey Institute of Technology; Rajesh Davé, New Jersey Institute of Technology
314d
Evaluation of Segregation Intensity of Pharmaceutical Blends Using Near Infrared Spectroscopy
Parind Desai, GlaxoSmithKline; Shreyas Acharya, GlaxoSmithKline; Kirby Amponsah-Manager, GlaxoSmithKline
314e
Quantification of Moisture Induced Cohesion in Pharmaceutical Powders at Different Humidity Conditions
Raj Mukherjee, UConn; Koyel Sen, UConn; Chen Mao, Genentech; Bodhisattwa Chaudhuri, University of Connecticut
314f
Powder Flow Analysis Using an Automated Milli-Scale Powder Flow Test
Trinkle David, Bristol Myers Squibb; Keirnan LaMarche, Patheon
314g
Understanding the Compression Behavior of Blends: The Application of Percolation Threshold Theory and Multivariate Analysis
Ana L. P. Queiroz, University College Cork; Abina Crean, University College Cork
Abstract Submissions Closed
See more of this Group/Topical: Pharmaceutical Discovery, Development and Manufacturing Forum
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