563 Emerging Tools and Enabling Technologies in Synthetic Biology: Design of Complex Circuits


Description:
Synthetic biology applies engineering principles to construct biological systems with unique and useful properties. The process of design and construction of these systems poses major challenges, owing to the complexity of biology. However, emerging tools have enabled the rapid construction of increasingly complex systems with predictable behaviors. This session will cover the development and application of these tools to the diverse topics of synthetic biology. Topics include, but are not limited to, DNA assembly, genetic circuit design and validation, modeling approaches, biomolecular breadboarding, synthetic regulation, cell-cell communication, RNA-based control schemes, and general understanding of biology that stems from design and construction of synthetic systems. Systems will span from in vitro experiments, viruses, diverse bacteria, and eukaryotes (yeast, mammalian cells, and plants). This session will focus particularly on the development of synthetic biology technology and approaches.

Sponsor:
Bioengineering


Chair:
Thomas J. Mansell
Iowa State University
Iowa State University
Chemical and Biological Engineering
Ames, IA
Phone Number: 515-294-7177
Email: mansell@iastate.edu

Co-Chair:
Nicholas R. Sandoval
Assistant Professor
Tulane University
Department of Chemical and Biological Engineering
ECCH 111
New Orleans, LA
80309
Email: nsandova@tulane.edu


Papers:
Investigation of Unique Interspecies Interactions in a Synthetic and Syntrophic Clostridium Co-Culture
Kamil Charubin, University of Delaware; Eleftherios Terry Papoutsakis, University of Delaware
Highly Multiplexed CRISPR-Cas9 Applications with Extra Long Sgrna Arrays
Alexander Reis, Penn State University; Sean Halper, Penn State University; Grace Vezeau, Pennsylvania State University; Daniel Cetnar, Penn State University; Ayaan Hossain, Pennsylvania State University; Phillip Clauer, Pennsylvania State University; Howard Salis, Penns State University
Synthetic Biology Framework for Engineering Post-Translational Circuits
Nichole Daringer, MIT; Caleb J. Bashor, Rice University; James Collins, MIT
Computational Modeling of Synthetic Gene Circuits to Improve Stem Cell Differentiation
Mihe Hong, Northwestern University; Joseph J. Muldoon, Northwestern University; Joshua N. Leonard, Northwestern University
An in vitro Transcriptional Regulatory Network for Modular Control of Synthetic Signals
Samuel Schaffter, Johns Hopkins University; Rebecca Schulman, Johns Hopkins University
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division