665 Gene Regulation Engineering: Medical and Biotechnological Tools and Applications


Description:
The regulation of gene expression dictates virtually all cellular processes with broad applications in biotechnology, medicine and synthetic biology. Controlling these processes requires a detailed understanding of the underlying gene regulatory mechanisms as well as approaches to manipulate existing or engineered regulatory interactions. For this session, we invite high-quality presentations that improve our ability to understand, predict, and control all aspects of gene expression through the quantitative characterization of its many molecular interactions. In addition, presentations on the construction and application of gene regulatory systems will be considered. Potential topics include regulation of transcription, translation, RNA stability, RNA processing, and post-translational modification as well as work that combines multiple gene regulatory systems to generate engineered genetic networks. Presentations that address gene regulation in industrial and medically relevant organisms particularly are encouraged.

Sponsor:
Bioengineering


Chair:
Anushree Chatterjee
Assistant Professor
University of Colorado Boulder
Chemical and Biological Engineering
Boulder, CO
80303
Email: chatterjee@colorado.edu

Co-chairs:
Lauren Woodruff
Assistant Professor
University of Massachusetts Amherst
Chemical Engineering
Amherst, MA
Email: lwoodruff@umass.edu

Albert Keung
Assistant Professor
North Carolina State University
Chemical and Biomolecular Engineering
Raleigh, NC
Email: ajkeung@ncsu.edu


Papers:
Development of a Genetic Toolkit in Rhodococcus Opacus PD630 for Reliable and Predictable Gene Expression
Drew DeLorenzo, Washington University in St. Louis; William R. Henson, Washington University in St. Louis; Austin Rottinghaus, Washington University in St. Louis; Tae Seok Moon, Washington University in St. Louis
Transcriptional Control through Synthetic Genetic Regulation Devices in Clostridium sensu Stricto
Nicholas R. Sandoval, Tulane University; Rochelle Joseph, Tulane University; Nancy Kim, Tulane University
Reprogramming of Liver Cell Lines to Definitive Endoderm By Understanding and Re-Engineering Developmental Master Regulatory Gene Circuits (DRGC)
Saber Meamardoost, University at Buffalo, State University of New York at Buffalo; Natesh Parashurama, University at Buffalo, State University of New York
mRNA Half-life Predictor: An in silico tool for Metabolic Engineers
Sanjan T.P. Gupta, Great Lakes Bioenergy Research Center; Gina C. Gordon, University of Wisconsin Madison; Parmeswaran Ramanathan, University of Wisconsin Madison; Brian F. Pfleger, University of Wisconsin Madison; Jennifer L. Reed, University of Wisconsin—Madison
Engineered Synbiotic Production and Sensing of Butyrate
Yanfen Bai, Iowa State University; Jenifer Saldanha, Iowa State University; Fatima Enam, Iowa State University; Jo Anne Powell-Coffman, Iowa State University; Thomas J. Mansell, Iowa State University
Rational Antimicrobial Engineering for Combating Multidrug-Resistant Pathogens
Anushree Chatterjee, University of Colorado Boulder
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division