317 Advances in Metabolic Engineering: Emerging Tools and Technologies


Description:
Metabolic engineering is the targeted improvement of the cellular metabolic phenotype using recombinant DNA technology. This session emphasizes pathway-level engineering. Approaches are typically mostly experimental and are focused on a specific pathway and metabolites rather than metabolism as a whole. Example areas include: strategies to enhance the production of natural products, pathway engineering for the production of novel products, and the application of evolutionary techniques for improving production of a metabolite. Abstracts describing new developments in these topics are sought, and the session is open to papers focused on any type of organism, microbial consortium, or cell-free system.

Sponsor:
Bioengineering


Chair:
Ryan Summers
Assistant Professor
The University of Alabama
Chemical and Biological Engineering
Tuscaloosa, AL
Phone Number: 2053487558
Fax Number: 205 348-7558
Email: rmsummers@eng.ua.edu

Co-chairs:
Kevin V. Solomon
Postdoctoral Scholar
University of California, Santa Barbara
Department of Chemical Engineering
Santa Barbara, CA
93106-5080
Phone Number: 7654941134
Email: kvs@purdue.edu

Mark Blenner
Assistant Professor
Clemson University
Chemical and Biomolecular Engineering
500 W 120th St
Clemson, SC
10027
Email: blenner@clemson.edu


Papers:
Automated Cellular Engineering of Saccharomyces Cerevisiae Strains with High Resistance and Production of Lactic Acid
Yajie Wang, UIUC; Tong Si, University of Illinois at Urbana Champaign; Huimin Zhao, University of Illinois at Urbana-Champaign; William Streyer, IGB
A Comparative Analysis of Single Cell and Droplet-Based FACS for Improving Production Phenotypes: Riboflavin Overproduction in Yarrowia Lipolytica
Leqian Liu, UCSF; James Wagner, UT Austin; Shuo-Fu Yuan, UT Austin; Maya Venkataraman, UT Austin; Adam Abate, University of California San Francisco; Hal Alper, The University of Texas at Austin
Utilization of the Endogenous Toxin Gene for Selection of High Performing Microbial Cells for Bioproduction Enhancement
Xiaonan Wang, Rutgers University; Avaniek Cabales, Rutgers University; Zhenghong Li, Rutgers University; Haoran Zhang, Rutgers University
Alleviation of Enzyme Product Inhibition By Genetic Biosensor-Based Evolution and Its Application in Enhanced Cis,Cis-Muconic Acid Production in Pseudomonas Putida
Ramesh Kumar Jha, Los Alamos National Laboratory; Niju Narayanan, Los Alamos National Laboratory; Scott Patrick Henelly, Los Alamos National Laboratory; Naresh Pandey, Los Alamos National Laboratory; Christopher Johnson, National Renewable Energy Laboratory; Gregg T. Beckham, National Renewable Energy Laboratory; Taraka Dale, Los Alamos National Laboratory
Cell-Free Prototyping Tools for Rapid Biosynthetic Pathway Engineering
Ashty S. Karim, Northwestern University; Michael Köpke, LanzaTech, Inc.; Michael C. Jewett, Northwestern University
­­­­­Syntrophic Co-Culture Amplification of Production Phenotype for High-Throughput Screening of Microbial Strain Libraries
Tatyana Saleski, University of Michigan; Alissa Kerner, University of Michigan; Meng Ting Chung, University of Michigan; Corine Jackman, University of Michigan; Azzaya Khasbaatar, University of Michigan; Katsuo Kurabayashi, University of Michigan; Xiaoxia (Nina) Lin, University of Michigan
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division