502 Combinatorial Techniques in Protein Engineering


Description:
This session will focus on the evaluation and implementation of combinatorial techniques for protein engineering. Relevant topics include combinatorial library design and synthesis, high-throughput screening and selection, and new methods for navigating complex biomolecular landscapes. Presentations pertaining to the extension of existing techniques (both theoretical and experimental) to new challenges in protein engineering are particularly encouraged.

Sponsor:
Bioengineering


Chair:
Arnab Mukherjee
Assistant Professor
University of California Santa Barbara
Chemical Engineering
Santa Barbara, CA
Phone Number: (805) 893-5137
Email: arnabm@engineering.ucsb.edu

Co-Chair:
Jerome M. Fox
Assistant Professor
University of Colorado, Boulder
Department of Chemical and Biological Engineering
12 Oxford Street
Boulder, CO
02138
Email: jerome.fox@colorado.edu


Papers:
502a
Biomolecular Engineering of Acoustomagnetic Protein Nanostructures for Non-Invasive Imaging of Cellular Function
George J. Lu, California Institute of Technology; Arash Farhadi, California Institute of Technology; Jerzy O. Szablowski, California Institute of Technology; Audrey Lee-Gosselin, California Institute of Technology; Samuel R. Barnes, Loma Linda University; Anupama Lakshmanan, California Institute of Technology; Raymond W. Bourdeau, California Institute of Technology; Mikhail G. Shapiro, California Institute of Technology
502b

Synthetic Electron Transfer Pathways As High-Throughput Selections for the Design of Protein Electron Carriers
Jonathan J. Silberg, Rice University

502c
Automating the Engineering of Improved Enzymes for Biomanufacturing
Emily Wrenbeck, Michigan State University; Matt Bedewitz, Michigan State University; Raisa Noshin, University of Virginia; Tim Whitehead, Michigan State University
502d
Constrained Combinatorial Libraries of Gp2 Proteins Enhance Discovery of Synthetic PD-L1 Ligands
Benjamin J. Hackel, University of Minnesota; Max A. Kruziki, University of Minnesota; Vidur Sarma, University of Minnesota
502e
Design of Glycosylation Sites By Rapid Synthesis and Analysis of Glycosyltransferases
Weston Kightlinger, Northwestern University; Liang Lin, Northwestern University; Madisen Rosztoczy, Northwestern University; Wenhao Li, Northwestern University; Matthew P. DeLisa, Cornell University; Milan Mrksich, Northwestern University; Michael C. Jewett, Northwestern University
502f
Elucidating the Evolvability of Ancestral Proteins Using a Continuous Stirred Tank Bioreactor
Daniel R. Woldring, HHMI/Brandeis University; Christopher Wilson, Broad Institute of MIT and Harvard; Dorothee Kern, HHMI/Brandeis University
502g
Synthetic Genetic Systems for Rapid Mutation and Evolution In Vivo
Chang Liu, UC Irvine
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
<< Previous Session | Next Session >>