684 Solid Form Selection: Cocrystals, Salts, Solvates, Polymorphs, and Beyond I


Description:
Continuous improvement of the physicochemical properties of active pharmaceutical ingredients (APIs) such as solubility, bioavailability, dissolution rate, stability, hygroscopicity, crystallinity and taste, represents an emerging area of research and development. This session focuses on the selection of solid forms including cocrystals, salts, solvates and polymorphs in crystallization processes, as well as the screening, predicting, manipulating and controlling techniques for such product selection.

Sponsor:
Crystallization and Evaporation
Co-Sponsor(s):
Food, Pharmaceutical & Bioengineering Division (15), Pharmaceutical Discovery, Development and Manufacturing Forum (26), Pharmaceuticals (15B), Particle Production and Characterization (03A)


Chair:
Fang Wang
Clover Crystallization

Phone Number: 650-619-9260
Email: fang.wang@CloverCrystallization.com

Co-chairs:
Marina Tsianou
Professor
University at Buffalo, The State University of New York (SUNY)
Department of Chemical and Biological Engineering
304 Furnas Hall
Buffalo, NY
14260-4200
Phone Number: (716) 645-1191
Fax Number: 716-645-3822
Email: mtsianou@buffalo.edu

Xiaobin Jiang
Associate Professor
Dalian University of Technology
Dalian
Email: xbjiang@dlut.edu.cn


Papers:
684a
Polymorphic Selection of Biominerals By Anionic Polyelectrolytes
Gopichand Mallam, University at Buffalo, The State University of New York (SUNY); Arkita Chakrabarti, University at Buffalo, The State University of New York (SUNY); Marina Tsianou, University at Buffalo, The State University of New York (SUNY)
684b
Coupling Experimental Results with Molecular Dynamics Simulations to Describe Polymorphism Obtained Using Solution Shearing
Stephanie Guthrie, University of Virginia; Baoxing Xu, University of Virginia; Yuan Gao, University of Virginia; Gaurav Giri, University of Virginia
684c
Investigation of the Polymorphy Phenomenon of the Carotene Lutein
Wei Guo, Tianjin University; Shijie Xu, Tianjin University; Shichao Du, Tianjin University; Lina Jia, Tianjin University; Yan Wang, Tianjin University; Junbo Gong, Collaborative Innovation Center of Chemical Science and Engineering; Xiaoyue Tan, Nankai University
684d
A Kinetic Study of Crystallization Process of Imatinib Mesylate with Polymorphic Transformation Phenomenon
Mengxing Lin, Western University; Sohrab Rohani, Western University
684e
Polymorphism of D-Mannitol: Selective Nucleation and Crystal Growth Mechanism
Weiyi Su, Hebei University of Technology; Chunli Li, Hebei University of Technology; Honghai Wang, National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization; Jing Fang, Hebei University of Technology
684f
Can the Solvation Manner Leads to a Nucleation Diversity for Polymorphic System? the Case of D-Mannitol
Shiyuan Liu, Tianjin University; Junbo Gong, Collaborative Innovation Center of Chemical Science and Engineering
684g
Insight into Solvent-Dependent Conformational Polymorphic Selectivity: A Case of Undecanedioic Acid
Peng Shi, Tianjin University; Shijie Xu, Tianjin University; Jingkang Wang, National Engineering Research Center for Industrial Crystallization Technology, School of Chemical Engineering and Technology, Tianjin University; Xiaoyue Tan, Nankai University; Junbo Gong, Collaborative Innovation Center of Chemical Science and Engineering
Introductory Remarks
Abstract Submissions Closed
See more of this Group/Topical: Separations Division
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