205 Agglomeration and Granulation Processes


Description:
This session seeks papers covering all aspects of Agglomeration and Granulation Processes, i.e., the process of forming larger granules from fine particles with or without the use of a binder; this includes wet-and melt-granulation, mixer-granulation, fluid bed granulation and coating and compaction under pressure. Papers are requested on theoretical, computer modeling and experimental research performed on the above systems; this includes fundamental physical and chemical aspects of agglomeration on granular, unit operation dynamics (e.g., flow and stress fields), system integration, scale-up and process control.

Sponsor:
Particle Production and Characterization


Chair:
James N. Michaels
Professor of Practice
University of Delaware
Chemical & Biomolecular Engineering
Newark, DE
Email: michaeja@udel.edu

Co-Chair:
Stephen L. Conway
Director
Merck & Co., Inc.
WP75B-210
West Point, PA
19486
Email: stephen_conway@merck.com


Papers:
Compartmental Modeling and Simulation Study of Wet Twin Screw Granulator
Gurmeet Kaur, Indian Institute of Technology Kharagpur; Themis Matsoukas, The Pennsylvania State University; Mehakpreet Singh, Bernal Institute, University of Limerick; Jitendra Kumar, Indian Institute of Technology Kharagpur
Developing a Formulation Dependent Mechanistic Kernel to Predict the Granule Size Distribution in a Two Component High Shear Wet Granulation Process
Indu Muthancheri, Rutgers The State University of New Jersey; Rohit Ramachandran, Rutgers The State University of New Jersey
A Model-Based Design of Experiment (MB-DOE) Approach Towards Scale-up of High Shear Wet Granulation Operation
Maitraye Sen, Eli Lilly and Company; Salvador García-Muñoz, Eli Lilly and Company
A Population Balance Based Rheological Model for Fresh Cement Paste
Juan Pablo Gallo-Molina, Ghent University; Ingmar Nopens, Ghent University; Karel Lesage, Ghent University
Agglomeration-Driven Product Selection in a Continuously Operated Fluidized-Bed Crystallizer
Andreas Voigt, OvG-University Magdeburg; Viktoria Wiedmeyer, OvG-University Magdeburg; Kai Sundmacher, Max Planck Institute for Dynamics of Complex Technical Systems
Roller Compaction Modelling: Pharmaceutical Application
Ricardo Sousa, R&D Drug Product Development; Slavomira Doktorovova, Hovione FarmaCiência SA; Vanessa Sainz, R&D Drug Product Development; Pedro Valente, Hovione FarmaCiência SA; Jean-Rene Authelin, Sanofi; Lionel Bardet, Sanofi
Anisotropic Mechanical Properties of Compacted Powders with Cohesive Contacts
Peter Loidolt, Technical University Graz; Johannes G. Khinast, Research Center Pharmaceutical Engineering
Abstract Submissions Closed
See more of this Group/Topical: Particle Technology Forum