298 Particle Engineering and Design for Product Value Enhancement


Description:
This session seeks papers whose scope is within the broadly defined area of Particle Engineering as applied in various industries such as pharmaceuticals, food, agrochemicals, cosmetics, etc. Various active agents or key functional ingredients are designed into particulate products in such a way to achieve controllable, reproducible, and effective functional responses in terms of product performance. These functional responses greatly depend on the dosage form and the way active agents and inert/excipient particles are integrated into the superstructure of the product. Particle engineering offers tools and methodologies, both experimental and numerical, to design the structure of particles so that the desired responses of the active agents are enhanced significantly in the dosage form. Particles and their surfaces can be designed and tailored in many different processes via different formulation approaches. Both novel formulations and the manufacturing processes that yield engineered particles are of interest to this session, as well as scientific approaches that relate particle formation, structure and functional performance. Papers can be experimental in nature, while fundamental theoretical or modeling works (e.g. based on DEM, FEM, CFD, or any combination in a multi-scale fashion) providing insight into the formation and behavior of the particles in the dosage form are also welcome.

Sponsor:
Particle Production and Characterization


Chair:
Ecevit Bilgili
Associate Professor
New Jersey Institute of Technology
Otto H. York Department of Chemical and Materials Engineering
161 Warren St. 150 Tiernan Hall
Newark, NJ
07102
Phone Number: 973-596-2998
Email: bilgece@njit.edu

Co-Chair:
Ilgaz Akseli
Director
Celgene
R&D Pharmaceutical Development
900 Ridgebury Rd
Summit, NJ
06877
Email: iakseli@celgene.com


Papers:
Carrier Based Dry Powder Inhaler Formulation – a Particle Engineering Perspective
Joana T. Pinto, Research Center Pharmaceutical Engineering GmbH; Sarah Zellnitz, Research Center Pharmaceutical Engineering GmbH; Eva Roblegg, University of Graz; Amrit Paudel, Research Center Pharmaceutical Engineering GmbH
Spray-Dried Nanocomposites and Amorphous Solid Dispersions with Identical Formulation for Comparative Assessment of Drug Dissolution Enhancement
Mahbubur Rahman, New Jersey Institute of Technology; Alexander Coelho, New Jersey Institute of Technology; Sayali Bhujbal, New Jersey Institute of Technology; Faustin Arevalo, New Jersey Institute of Technology; Ecevit Bilgili, New Jersey Institute of Technology
Fabrication of Biodegradable Rod-Shaped Drug Carriers with Modified Two-Step Emulsion Solvent Evaporation Technique
Hanieh Safari, University of Michigan; Reheman Adili, University of Michigan; Michael Holinstat, University of Michigan; Omolola Eniola-Adefeso, University of Michigan
Surface Engineering of Lactose Particles By Atomic Layer Deposition for Modified Release
Damiano La Zara, Delft University of Technology; Di Zhang, AstraZeneca R&D Gothenburg; Mike J. Quayle, AstraZeneca R&D Gothenburg; Gunilla Petersson, AstraZeneca R&D Gothenburg; Staffan Folestad, AstraZeneca R&D Gothenburg; J. Ruud van Ommen, Delft University of Technology
Improving Blend and Tablet Properties of Binary Mixtures Containing Cohesive and Poorly-Compactable APIs Using Surface Engineered MMC Based Fine Excipients
Liang Chen, New Jersey Institute of Technology; Xiaoyi Ding, New Jersey Institute of Technology; Siqi Fan, New Jersey Institute of Technology; Zizhou He, New Jersey Institute of Technology; Rajesh Davé, New Jersey Institute of Technology
Determination of Flow and Compressibility Properties of Pharmaceutical Powders: Effect of Fines and High Drug Loading
Patrick Cronin, Bernal Institute, University of Limerick; Bernardo Castro Dominguez, Bernal Institute, University of Limerick; Barbara Schaller, Bernal Institute, University of Limerick; Kevin Moroney, Bernal Institute, University of Limerick; Denise Croker, Bernal Institute, University of Limerick; Ahmad Albadarin, University of Limerick; Gavin Walker, University of Limerick
Formulation of Microcarriers for Levodopa Delivery Via the Pulmonary System
Mahasweta Paul, Nanyang Technological University; Raymond Lau, Nanyang Technological University
Surface Modification to Improve Drug-Excipient Mixing for DPI Formulation
Neetu Varun, Indian Institute of Technology Gandhinagar; Chinmay Ghoroi, Indian Institute of Technology Gandhinagar
Impregnation of Catalysts with Viscous Metal Solutions Using Experiments and DEM Simulations
M. Silvina Tomassone, Rutgers University; Yangyang Shen, Rutgers University; Jiao Yang, Rutgers University; William G. Borghard, Rutgers, the State University of New Jersey
Abstract Submissions Closed
See more of this Group/Topical: Particle Technology Forum