643 Advances in Metabolic Engineering of Autotrophic Organisms


Description:
Non-traditional host systems provide diverse genetic backgrounds and metabolic capabilities, which can serve as advantageous production platforms for a wide range of pharmaceuticals, biochemicals and biofuels. This session will focus on metabolic engineering efforts in non-model organisms (e.g. plants, fungi, algae, cyanobacteria, archaea, and non-model bacteria). Sample topic areas of interest include synthetic biology/molecular tool development, metabolic flux analysis, construction and analysis of genome scale models, application of "omics" techniques, and production of novel products through pathway and genome engineering.

Sponsor:
Bioengineering


Chair:
Nanette R. Boyle
Colorado School of Mines
Chemical and Biological Engineering
1500
Golden, CO
80401
Email: nboyle@mines.edu

Co-chairs:
Robert Jinkerson
University of California Riverside

Email: Robert.Jinkerson@ucr.edu

Arul Varman
Arizona State University

Email: Arul.M.Varman@asu.edu

Hsien-Chung Tseng
Head of Strain Development
Manus Bio
Cambridge, MA
Email: hctseng@manusbio.com


Papers:
Transcriptional Regulators for Predictable and Precise Gene Expression in the Metabolically Versatile Rhodopseudomonas Palustris CGA009
Cheryl Immethun, University of Nebraska; Dianna Long, University of Nebraska; Rajib Saha, University of Nebraska-Lincoln
Methane-Limited Vs Oxygen-Limited Growth of Methylomicrobium Buryatense 5GB1: a Systems Approach
Kyle Stone, Auburn University; Q. Peter He, Auburn University; Jin Wang, Auburn University
Model-Guided Engineering of Cyanobacteria for Stable, High-Yield Biofuel Production
Hugh Purdy, University of Wisconsin-Madison; Jennifer Reed, University of Wisconsin Madison
Development of Genetic Tools for the Biomining Bacterium, Acidithiobacillus Ferrooxidans
Yuta Inaba, Columbia University; Timothy Kernan, Columbia University; Indrani Banerjee, Columbia University; Alan C. West, Columbia University; Scott Banta, Columbia University
Model-Guided Metabolic Engineering of Increased 2-Phenylethanol Production in Plants
Shaunak Ray, Purdue University; Joseph Lynch, Purdue University; Clint Chapple, Purdue University; Natalia Dudareva, Purdue University; John A. Morgan, Purdue University
Developing Genome-Scale Whole-Plant Models for Poplar (Populus deltoides) and Switchgrass (Panicum virgatum)
Patrick F. Suthers, The Pennsylvania State University; Debolina Sarkar, The Pennsylvania State University; Costas Maranas, The Pennsylvania State University
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division