702 Engineering in Cancer Biology and Therapy II: Tumor Microenvironment and Mechanics


Description:
This session will cover a broad spectrum of approaches engineers have developed to understand and treat cancer. Abstracts could include include studies on fundamental biological processes involved in the development of cancer and in diagnosis or therapy of cancer. Experimental systems and computational approaches can range from microorganisms to mammalian cells to multi-cellular organisms (Drosophila and worms) and animal models, with a focus on the intersection between engineering and cancer.

Sponsor:
Engineering Fundamentals in Life Science
Co-Sponsor(s):
Biomaterials (08B)


Co-chairs:
Matthew Paszek
Cornell University
Smith School of Chemical and Biomolecular Engineering
Ithaca, NY
Email: mjp31@cornell.edu

Marjan Rafat
Vanderbilt University
Chemical and Biomolecular Engineering
Nashville, TN
Email: marjan.rafat@vanderbilt.edu


Papers:
702a
Characterizing Interstitial Fluid Flow and the Effects of Shear Stress in the Brain Tumor Microenvironment
R. Chase Cornelison, Virginia Polytechnic Institute and State University; Kathryn M. Kingsmore, University of Virginia; Caroline E. Brennan, University of Virginia; Steven Tom, Virginia Polytechnic Institute and State University; Jennifer M. Munson, Virginia Polytechnic Institute and State University
702b
Tissue Architectural Cues and Differential Extravasation Patterns Drive the Non-Random Trafficking of Tumor Cells in Larval Zebrafish
Colin D. Paul, National Cancer Institute; Kevin Bishop, National Human Genome Research Institute; Alexus Devine, National Cancer Institute; William J. Wulftange, National Cancer Institute; Elliott L. Paine, National Cancer Institute; Jack R. Staunton, National Cancer Institute; Steven Shema, National Cancer Institute; Val Bliskovsky, National Cancer Institute; Lisa M. Miller Jenkins, National Cancer Institute; Nicole Y. Morgan, National Institute of Biomedical Imaging and Bioengineering; Raman Sood, National Human Genome Research Institute; Kandice Tanner, National Cancer Institute
702c
Perinuclear Actin Flow Promotes Efficient Cell Migration in Confinement
Panagiotis Mistriotis, Johns Hopkins University; Emily Wisniewski, Johns Hopkins University; Yizeng Li, Johns Hopkins University; Robert Law, Johns Hopkins University; Kaustav Bera, Johns Hopkins University; Soontorn Tuntithavornwat, Johns Hopkins University; Alexandros Afthinos, Johns Hopkins University; Runchen Zhao, Johns Hopkins University; Sean X. Sun, Johns Hopkins University; Petr Kalab, Johns Hopkins University; Konstantinos Konstantopoulos, Johns Hopkins University
702d
Enhanced Capture and Release of Circulating Tumor Cells Using Hollow Glass Microspheres with Nanostructured Surface
Ziye Dong, Texas Tech University; Dan Yu, Texas Tech University; Wei Li, Texas Tech University
702e
A Cell-Friendly 3D Culture System for Scalable Culturing of Primary Human Glioblastoma Tumor-Initiating Cells
Qiang Li, University of Nebraska, Lincoln; Haishuang Lin, University of Nebraska, Lincoln; Ou Wang, University of Nebraska-Lincoln; Yuguo Lei, University of Nebraska - Lincoln
702f
Computational Study of Microscopic Drug Transport and Distribution in Tumor Vasculature
Moath Alamer, Imperial College London; Xiao Yun Xu, Imperial College London
702g
Invited Speaker: Engineering Microenvironments for Probing and Manipulating Cellular Mechanical Activities
Yu-li Wang, Carnegie Mellon University
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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