692 Solid Form Selection: Cocrystals, Salts, Solvates, Polymorphs, and Beyond

Friday, November 20, 2020: 8:00 AM - 9:00 AM
Separations Division (02) (PreRecorded+)

Description:
Continuous improvement of the physicochemical properties of active pharmaceutical ingredients (APIs) such as solubility, bioavailability, dissolution rate, stability, hygroscopicity, crystallinity and taste, represents an emerging area of research and development. This session focuses on the selection of solid forms including cocrystals, salts, solvates and polymorphs in crystallization processes, as well as the screening, predicting, manipulating and controlling techniques for such product selection.

Sponsor:
Crystallization and Evaporation
Co-Sponsor(s):
Food, Pharmaceutical & Bioengineering Division (15), Pharmaceutical Discovery, Development and Manufacturing Forum (26)
Chair:
Gaurav Giri Email: gg3qd@virginia.edu
Co-Chair:
Srividya Ramakrishnan Email: srividyar@drreddys.com


(692a) A Systematic Study of State-of-the-Art Methods in Crystal Structure Prediction for Organic Hydrates
Yizu Zhang, Isaac J. Sugden, Susan M. Reutzel-Edens, Constantinos C. Pantelides and Claire S. Adjiman


(692c) Effects of Inorganic Salts and Volume Reduction on Glycine Polymorphism
Isaac Jerome C. Dela Cruz, Gerard Capellades, Jem Valerie D. Perez, Bryan G. Alamani and Allan S. Myerson



See more of this Group/Topical: Separations Division