Abstract: Synthesis of Biocompatible Photoluminescent Hybrid Particles (SBE’s 6th International Conference on Bioengineering and Nanotechnology)

Hyun Chang Kim, Department of Chemical & Biomolecular Engineering, Yonsei University, Seoul, South Korea, Hoon Choi, Chemical and Biomolecular Engineering, Yonsei University, Seoul, South Korea, Heeyoung Ahn, Yonsei University, Seoul, South Korea and Kangtaek Lee, Department of Chemical Engineering, Yonsei University, Seoul, South Korea

Synthesis of biocompatible photoluminescent hybrid particles

Hyun Chang Kim, Hoon Choi, Heeyoung Ahn, and Kangtaek Lee

Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, 120-749, Korea

ABSTRACT

Quantum dot nanoparticles have gathered wide attention for their narrow emission spectrum, intense luminescence and high stability against photobleaching compared with organic dyes. A drawback remains that quantum dot is highly toxic and needs to be modified before being used for biological applications. This study presents a method to easily fabricate biocompatible photoluminescent hybrid particles using quantum dots. Silica@QD@Silica particles are synthesized in organic solvent phase which is then transferred to aqueous phase. The synthesized hybrid particles have a silica surface for a wide range of surface modification, excellent biocompatibility, and higher photoluminescence efficiency compared to water soluble quantum dots. Another merit of the hybrid particles is the size controllability, allowing for various applications with different sizes while preserving the particle properties.

Keywords: Quantum dots, Silica particles, Biocompatible

Extended Abstract: File Not Uploaded

See more of this Session: Poster Session
See more of this Group/Topical: 6th International Conference on Bioengineering and Nanotechnology