| Application of Micro-Reactor Technology in Process Development | ||
| Xini Zhang, Chemical & Pharmaceutical Development, Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 1000 Rt. 202, Raritan, NJ 08869 The microreactor technology is an efficient tool for kilogram scale syntheses in continuous mode and is particularly effective for hazardous reactions that do not allow scale up in conventional reactors. Applications to several classes of reactions including highly exothermic reactions, high temperature reactions, reactions with unstable intermediates and reactions involving hazardous reagents are discussed. Extended Abstract Status: Not Uploaded | ||