Particle Technology Applications to Pharmaceutical Continuous Processes I


Description:
The development and application of continuous processes in pharmaceutical drug product has increased in recent years. Particle technology principles can play a key role in the development of continuous processes as they can provide a theoretical basis for design. This session invites papers focused on the applications of particle technology for drug product continuous processes. Examples of these include case studies on process development, development of mathematical modeling for continuous unit operations, development of advanced process control methodologies, and application of innovative real-time analytics techniques.

Sponsor:
Applications of Particle Technology for Pharmaceuticals


Chair:
Aditya Vanarase
Celgene

Email: avanarase@celgene.com

Co-Chair:
Luke Schenck
Senior Chemical Engineer
Merck & Co, Inc.
Chemical Process Development and Commercialization
126 E. Lincoln Highway
Rahway, NJ
07065-0900
Email: luke_schenck@merck.com


Papers:
Investigation of Different Continuous Drying Routes for Pharmaceuticals
Manuel Kreimer, Research Center Pharmaceutical Engineering; Manuel Zettl, Research Center Pharmaceutical Engineering; Isabella Aigner, Research Center Pharmaceutical Engineering; Stephan Sacher, Research Center Pharmaceutical Engineering; Markus Krumme, Novartis Pharma AG; Thomas Mannschott, Novartis Pharma AG; Peter van der Wel, Hosokawa Micron B.V.; Albert Kaptein, Hosokawa Micron B.V.; Johannes G. Khinast, Research Center Pharmaceutical Engineering GmbH
A Systematic Study of Liquid and Solid Residence Time Distributions in a Dynamic Baffle Crystallizer
Claire Yiqing Liu, Purdue University; Alastair Barton, Alconbury Weston Ltd; Paul Firth, Alconbury Weston Ltd; Jonathon Speed, Keit Spectrometers; Dan Wood, Keit Spectrometers; Zoltan K. Nagy, Purdue University
The Axial Dispersion Coefficient Performance in a Novel Oscillatory Flow Reactor with Liquid Solutions and Solids Suspensions – a Design of Experiments Approach
Patrícia Cruz, LEPABE – Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering of the University of Porto; Carolina Silva, LEPABE – Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering of the University of Porto; Fernando Rocha, LEPABE; António Ferreira, LEPABE – Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering of the University of Porto
Relative Contribution of Cohesion and Internal Friction to Flowability of Pharmaceutical Powders
Lap Yin (Henry) Leung, Genentech Inc; Chen Mao, Genentech; Chia-Yi Yang, Genentech Inc; Ishan Srivastava, Sandia National Laboratories; Ping Du, Catalent Pharma Solutions
Abstract Submissions Closed