Modeling of Pharmaceutical Unit Operations I


Description:
The application of mathematical modeling tools in pharmaceutical development has increased in recent years. These tools can enable process design, optimization and troubleshooting of processing problems. This session seeks contributions showcasing the development and implementation of first-principles as well as data-driven process modeling, simulation and optimization methods for unit operations involved in pharmaceutical drug product. Modeling approaches including CFD, DEM, FEM, PBM, Monte Carlo and other phenomenological methods are welcome.

Sponsor:
Applications of Particle Technology for Pharmaceuticals
Co-Sponsor(s):
Applications of Solids Processing Unit Operations (T12)


Chair:
Chi-Hwa Wang
Professor
National University of Singapore
Department of Chemical and Biomolecular Engineering
M3TC Research Center
Singapore
117576
Phone Number: +65 65165079
Fax Number: 65-67791936
Email: chewch@nus.edu.sg

Co-chairs:
Benjamin J. Glasser
Professor
Rutgers University
Dept. of Chemical and Biochemical Engineering
Chemical and Biochemical Engineering
Piscataway, NJ
08854
Fax Number: 732-445-2581
Email: bglasser@rutgers.edu

Carl Wassgren
Professor
Purdue University
School of Mechanical Engineering
West Lafayette, IN
47907
Email: wassgren@purdue.edu


Papers:
Validation of CFD-DEM Simulation of a Continuous Tablet Coating Process
Peter Boehling, Research Center Pharmaceutical Engineering; Stefan Mohr, RCPE; Frederik Detobel, GEA; James Holman, GEA; Matthew Metzger, Merck Sharp & Dohme Corp; Laura Wareham, Merck Sharp & Dohme Corp.; Sean McClure, Merck Sharp & Dohme Corp.; Johannes G. Khinast, Research Center Pharmaceutical Engineering GmbH
Modelling of High Shear Wet Granulation Using a Population Balance Framework
Stefan Bellinghausen, University of Sheffield; Dana Barrasso, Process Systems Enterprise; Emmanuela Gavi, F. Hoffmann - La Roche Ltd; Laura Jerke, F. Hoffmann-La Roche AG; Agba Salman, University of Sheffield; James D. Litster, The University of Sheffield
Prediction of Pressure Filtration Performance in Systems with Pharmaceutical High Aspect Ratio Crystals
Ioannis S. Fragkopoulos, University of Leeds; Bilal Ahmed, AstraZeneca; Claire MacLeod, AstraZeneca; Frans L. Muller, University of Leeds
CFD Modelling of Drying and Crystalline Transformation in a Co-Current Spray Dryer
Andrew E. Bayly, University of Leeds; Muzammil Ali, University of Leeds; Tariq Mahmud, University of Leeds; Peter Heggs, University of Leeds
Abstract Submissions Closed