Paper No. 31998-208710
EPIDEMIOLOGICAL INDICATORS OF AN ENVIRONMENTAL EXPOSURE TO CARCINOGENIC MINERAL FIBERS IN SOUTHERN NEVADA

BAUMANN, Francine1, BUCK, Brenda2, YANG, Haining3, METCALF, Rodney V.4, GAUDINO, Giovanni3, REN, Minghua5, and CARBONE, Michele3, (1) University of Hawaii Cancer Center, 651 Ilalo Street, Suite BSB231, Honolulu, HI 96813, fbaumann@cc.hawaii.edu, (2) Department of Geoscience, University of Nevada Las Vegas, 4505 South Maryland Parkway, Box 454010, Las Vegas, NV 89154-4010, (3) University of Hawaii Cancer Center, 651 Ilalo St, BSB Rm231, Honolulu, HI 96813, (4) Department of Geoscience, University of Nevada, Las Vegas, 4505 S. Maryland Parkway, Las Vegas, NV 89154-4010, (5) Dept. Goesciences, UNLV, Las Vegas, NV 89154-4010
Inhalation of asbestos fibers is known to cause highly fatal diseases, including asbestosis, lung cancer and more specifically malignant mesothelioma (MM). Due to occupational exposure, MM occurs generally 4-8 times more frequently in men than in women, at the median age of 74 years. Recent studies showed that several non-regulated mineral fibers are as carcinogenic as the regulated asbestos. Growing population and human activities in rural areas may expose the population to carcinogenic fibers released from disturbed fibrous minerals.

Nevada is among the states having the highest MM incidence, while asbestos was not produced in this state. Analysis of data from the Nevada Central Cancer Registry indicates that Clark County has abnormally high incidence of exceptionally young MM cases, with a significant low M:F sex ratio. In addition, Nevada shows the highest rates of lung cancer incidence and mortality in women among the western states. High incidence of young lung cancer was recorded in both genders in Clark County. These indicators reveal that an environmental exposure to carcinogenic mineral fibers is very likely the cause of these preventable diseases in Southern Nevada.

Environmental exposure to mineral fibers can happen if 1) there are deposits of fibrous minerals in the natural environment, 2) human activities or high weathering release these fibers in the air, and 3) human population is in contact with the airborne fibers. Several asbestiform minerals were found in the natural environment of Southern Nevada area, including the highly carcinogenic erionite as well as the amphiboles winchite and magnesioriebeckite that have been associated with asbestos-related diseases in Libby, Montana, and other possibly carcinogenic fibrous minerals. The expansion of the human population in Southern Nevada has developed traffic and off-road recreational activities. Dust eroding off of adjacent Federal Lands is likely a major source of those hazardous mineral fibers in Clark County.

Our trans-disciplinary research aims to identify the high-risk areas, sources of fibrous minerals, activities responsible for the release of the fibers, high-risk population, study the carcinogenicity of the different mineral fibers present in the area, and propose strategies to prevent environmental exposure.

Discipline Categories: Geology and Health

Preferred Presentation Type: Oral