Introducing YABI Workflow Environment and its Applications for Personalised Medicine and Food Security

Advances in next generation sequencing (NGS) technologies have made the prospect of sequencing an individual's genome for diagnostic purposes and sequencing a large complex genome such as the wheat genome realistic in the very near future. It is easy to think this means the information from this data would be available for immediate use, but here in lies the bottleneck. High throughput data processing requires a bioinformatics environment that is user-friendly, highly customizable, and leverages transparently local, super- or cloud computing infrastructure automatically for the end user.

In this presentation we introduce Yabi a web-based analytical environment framework for bioinformatics applications that can be customized for a diverse range of -omics applications including genomics, transcriptomics, metagenomics, proteomics and/or metabolomics.

Yabi primarily enables seamless and transparent access to heterogenous HPC and cloud resources and then builds an analysis workflow environment that can create and reuse workflows. Yabi is able to manage large amounts of both raw and processed data in a secure and flexible way across geographically distributed compute resources. Users are able to either use the web-based environment to drag-and-drop tools to create sophisticated workflows or alternatively use the yabi-command-line, which is designed for users more comfortable writing scripts or for configuring external workflow environments. Yabi greatly simplifies the task of configuring tools by enabling system administrators to configure as well as manage running tools via a web-based environment and without the need to write/edit software programs/scripts. Yabi may be found at: http://ccg.murdoch.edu.au/yabi/.