The European Variation Archive at EMBL - EBI

EMBL-EBI has launched a brand new genetic variation resource: The European Variation Archive (EVA; www.ebi.ac.uk/eva). EVA archives all types of variation data from all species and currently more than 40% of all data in EVA is from non-human species, mostly plant and livestock. We aim to provide a resource to the plant and animal community that can accession, archive and provide views of genetic variation data more quickly and in a more granular manner than any other resource of this nature, worldwide. 

Variants stored at EVA are annotated using a variety of standardized methods, including Ensembl’s Variant Effect Predictor. We shall present the ways in which users can mine these data using filters on the website to construct both study-centric and global queries, filtering on any combination of species, methodology, variant type, phenotype, consequence or allele frequency and how results from these queries can be downloaded in a variety of formats including VCF and CSV. Additionally, EVA provides a comprehensive RESTful web-service, to allow programmatic access, and hence the integration of these data with other resources such as Ensembl Variation and Uniprot, and this shall also be presented.