High Throughput DNA Extraction, WGA and Targeted Next Generation Sequencing (NGS)

Agriculture, bioindustry and project support services play an increasingly important role in genomics research across a range of disciplines including food and health science, and studies relating to environmental sustainability. Bringing together different techniques and applications from sampling, storage and preparation to analysis and data interpretation has become key in delivering services to support genomics research.

Similarly, expanded sequencing capacity is delivering new regions of interest for genome analysis, and the links between AgBio industry and research and next generation sequencing laboratories have become crucial elements in successful molecular assisted breeding as NGS technologies have grown to complement and replace Sanger sequencing. In turn, the needs for NGS sample preparation and processing speed have become key parts of many research projects.

To meet these new challenges LGC Genomics has expanded laboratory capacity to enable delivery of high throughput DNA extraction with full QC and sample normalisation support married to follow on services for SNP and InDel marker genotyping, amplicon based targeted re-sequencing (aTRS) and mitochondrial aTRS. Our whole genome amplification service also plays an important role in many projects where expansion of stored DNA and the development of specific marker assays for use in future studies is required.

This publication provides a brief overview of the range of technologies and instrumentation solutions which LGC Genomics delivers for global genetic research in the areas of sample preparation, whole genome amplification, genotyping and DNA sample storage.