C04
Sequence Viewer and Genome Workbench - Sequence Display and Analysis Tools

Date: Saturday, January 10, 2015
Time: 2:30 PM
Room: California
Kim D. Pruitt , National Center for Biotechnology Information (NCBI/NLM/NIH), Bethesda, MD
Robert Falk , NIH/NLM/NCBI, Bethesda, MD
Michael DiCuccio , National Center for Biotechnology Information, Bethesda, MD
Terence Murphy , NIH/NLM/NCBI, Bethesda, MD
Anatoliy Kuznetsov , National Center for Biotechnology Information, Bethesda, MD
The National Center for Biotechnology Information (NCBI) has developed two companion tools to display and analyze sequence and alignment data. Sequence Viewer is an online graphical display tool that offers configurable options for displaying NCBI as well as imported BLAST or local data. This online tool includes options to add and configure display tracks, zoom and pan the display, add (and name) markers, search, download the displayed sequence, and save a high-resolution print friendly PDF file that can be edited in popular image editing tools for figure preparation. Sequence Viewer graphical displays are available from BLAST, Gene, Nucleotide, Protein, Epigenomics, and other NCBI resources (for example, the cow biglycan gene www.ncbi.nlm.nih.gov/gene/280733).  Genome Workbench is an integrated application for viewing and analyzing sequence and alignment data.  The application is available for multiple platforms (http://www.ncbi.nlm.nih.gov/tools/gbench/) and is supported by extensive online documentation including YouTube tutorials. NCBI data ranging from a single accession to a whole genome can be loaded into the application across an internet connection by query, or local annotation or alignment files can be imported.  The application supports multiple display options including graphical annotation displays, dot plots, multiple alignments, phylogenetic trees and integrates tools for generating alignments.  Genome Workbench also supports comparative views of downloaded NCBI data and local annotation data of the same sequence. This presentation will provide an overview of both tools.