Mechanism and Influence of Early Developmental Capacity in Bovine Reconstructed Embryos in Somatic Cell Nuclear Transfer

To elucidate developmental mechanisms of reconstructed embryos in somatic cell nuclear transfer, the early developmental capacity of bovine embryos is a vital period. Developmental mechanism and influences from different aspects are presented in this paper. Influences of early developmental bovine embryos are further discussed in laboratory protocols of Utah State University in this research.

Through decreasing various influences in entire developmental process of bovine reconstructed embryos, it will improve the early developmental capacity and facilitate the technological application of somatic cell nuclear transfer as a research method in animal industries, such as, rescue of extinct animals and rare species, research in differentiation of embryonic stem cells, replacement of organs, embryonic gene expression, mediation of post-transcription and post-translation of DNA, epigenetic expression and genome expression in early reconstructed embryos. It is significant to integrate somatic cell nuclear transfer into other biotechnologies for problem-solving in human beings and all creatures.

Somatic nuclear transfer has huge potential on deepening investigating some gradually serious diseases that are related humans’ health. By inducing genomes of diseases into the reconstructed embryos to cause diseases later in animals’ growth stage, both embryonic developments and disease’s dynamic changes in morphology, structural function and metabolic pathway will be monitored from an individual embryo to an adult. For making effective medical treatments early instead of loss the control to deadly diseases’ outbreak in globally, such as, cancers, tumors, cardiovascular diseases, respiratory diseases, hematologic disease, contagious diseases, etc. it is prospective in comprehensive collaboration of scientific researching technologies in animal sciences, life sciences, wellness industry, biomedicines and pharmaceutical industries in globalization.