NCBI Genomic Data Viewer

The National Center for Biotechnology Information (NCBI) has developed a new browser resource, the Genomic Data Viewer (GDV), to display and analyze genome assemblies for a wide variety of organisms. Built on NCBI’s existing browser technology used for the Variation Viewer and 1000 Genomes Browser, GDV makes use of the wealth of sequence associated data stored at NCBI to provide browser tracks and also supports displays for other datatypes, such as genotypes and allele frequencies. In addition to the display of NCBI-provided tracks, GDV supports the upload and display of user-provided data, accepting a variety of common file formats. GDV browser instances are available for any RefSeq assembly in the NCBI Assembly database that has track data. NCBI resources that refer out to GDV can customize the default track display to include the tracks most relevant to their content area. For instance, GDV referrals from NCBI Variation resources can be configured to show SNVs and structural variations from dbSNP and dbVar in genomic context with gene annotations, and a dynamic table of sample genotypes and population allele frequency. In addition, the browser display is easily user-configured, either to custom track combinations or with preset combinations of tracks relevant to various analysis types. Track configurations can be saved and shared with other users. This presentation will demonstrate some of the available functionality in GDV, including searching, navigating, accessing and configuring tracks, uploading user data, and provide examples of the flexible use of the GDV at NCBI.