Methods: Between September 2025- January 2026, we conducted a convergent mixed methods study using surveys and focus groups with clients and personnel from eight different HIV care organizations across Southern U.S. Surveys assessed exposure to EWE in the last three years and their impact on HIV services. Focus groups (1-9 participants/per group) explored lived experiences and practices to contextualize findings and were analyzed using content analysis. Logistic regression was used to evaluate the association between poverty and patient care.
Results: Study participants spanned the HIV Prevention and Care Continuum, including individuals from a mobile syringe exchange, HIV home testing, pre-exposure prophylaxis (PrEP) services, standard HIV care, and behavioral health care. Twenty-four focus groups were conducted, including 71 clients and 70 personnel (groups ranging between 1-9 participants). The quantitative surveys suggested self-identified exposure to EWE was pervasive amongst both clients (160/284, 56%) and personnel (165/205, 80%). Personnel reported significant perceived disruptions to clients’ ability to access needed medical care in general (71%) and 60% to clients’ access to HIV care or prevention services. Of the clients experiencing EWE, 41% reported disruptions to needed medical care in general and 23% to their HIV-related services. Also, 16% reported missing doses of PrEP or Antiretroviral Therapy. Among clients experiencing EWE, after adjustment for age, sex, education, and race, clients with greater difficulty paying for basic needs were more likely to report disruptions in needed medical care overall (Odds Ratio (OR): 2.86, 95% confidence interval (CI): 1.39-5.86, p-value = 0.004) and HIV care/ prevention services (OR=3.69, 95% CI: 1.57-8.67, p-value = 0.003). Qualitative findings identified key drivers of disruption, including clinic closures, canceled services, power and internet outages, staffing shortages, and transportation barriers, particularly in rural areas. A key theme was a gap between staff safety/emergency protocols during inclement weather and client access to essential services. Interruptions in syringe exchange services led some individuals to reuse unsafe needles. Some organizations already employ mitigation tactics (e.g., multi-month supplies of PrEP and ART, mail-order pharmacy options, provision of continuous care or crisis response options during and after events, and flexible scheduling). However, these mitigation approaches were unevenly available, underscoring that those with the least resources may be most vulnerable to disruptions.
Conclusions: Both clients and personnel reported perceiving there were care disruptions related to EWEs. Personnel reported higher awareness of disruptions, possibly reflecting efforts to shield clients from impacts. The study identifies practical mitigation strategies that could be standardized into shared guidelines to strengthen climate-resilient HIV prevention and care. Social work research is well positioned to support these efforts by addressing the structural and social drivers of health disparities.
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