Recent field applications have emphasized the need for method and knowledge to understand the synergy between flow and reactive transport in subsurface systems. Multiple physical and chemical processes occur at different scales: precipitation, dissolution, geochemical reactions, non-reactive mineral releasing, clogging of the fractures, phase change of solid phase etc. Mechanistic understanding of (1) how multiple processes couple with each other, and (2) how small scale fluid-solid interaction translates to larger scale is crucial for establishing predictive models at macroscopic scale. Novel experimental and characterization techniques become available to elucidate the coupling between hydrodynamics, reactive transport and topology from nano to field scales. This session will gather recent advances in experiments and theoretical analysis that involve multi-scale reactive transport processes in porous and fractured media. We encourage experimental and characterization results unveiling strong interplay between multiple processes at different scales.