Degradable Polymersomes That Create New Pathways for Anti-Cancer Drugs
Fariyal Ahmed1, Refika I. Pakunlu2, Goundla Srinivas3, Michael L. Klein3, Tamara Minko2 and Dennis E. Discher4, (1)Bioengineering, University of Pennsylvania, 220 South 33rd Street, Room 112 Towne Bldg., Philadelphia, PA 19104-6391, (2)Ernest Mario School of Pharmacy, Department of Pharmaceutics, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, (3)Chemistry, Univ.Pennsylvania, 112 Towne Bldg, Philadelphia, PA 19104, (4)Chemical & Biomolecular Engineering, University of Pennsylvania, 220 South 33rd Street, Room 112 Towne Bldg., Philadelphia, PA 19104-6391 |
Breaking down Endolysosomal Barriers for Drug Delivery with Degradable Polymersomes
Fariyal Ahmed, Bioengineering, University of Pennsylvania, 220 South 33rd Street, Room 112 Towne Bldg., Philadelphia, PA 19104-6391, Goundla Srinivas, Univ.Pennsylvania, Dept.Chemistry, Philadelphia, PA 19104, Aaron Brannan, Department of Chemical Engineering & Material Science, University of Minnesota, Minneapolis, MN 55455, Michael L. Klein, Chemistry, Univ.Pennsylvania, 112 Towne Bldg, Philadelphia, PA 19104, Frank S. Bates, University of Minnesota, 421 Washington Avenue SE, Minneapolis, MN 55455 and Dennis E. Discher, Chemical & Biomolecular Engineering, University of Pennsylvania, 220 South 33rd Street, Room 112 Towne Bldg., Philadelphia, PA 19104-6391 |
Controlled Transdermal Nicotine Delivery with Aligned Carbon Nanotube Membrane
Bruce J. Hinds, University of Kentucky, 177 Anderson Tower, CME-0046, Lexington KY, KY 40506-0046, Audra Stinchcomb, Coll. of Pharmacy, University of Kentucky, 177 Anderson Tower, CME-0046, Lexington KY, KY 40506-0046, Mainak Majumder, Chem. & Mater. Eng., University of Kentucky, 177 Anderson Tower, CME-0046, Lexington KY, KY 40506-0046 and Nitin Chopra, Chem & Mater. Eng., University of Kentucky, 177 Anderson Tower, CME-0046, Lexington, KY 40506-0046 |
Real-Time Transport of Polymer Nanoparticles in Cervical Vaginal Mucus
Samuel K. Lai1, Elizabeth D. O’Hanlon2, Stan T. Man1, Richard Cone2 and Justin Hanes1, (1)Chemical & Biomolecular Engineering, Johns Hopkins University, 221 Maryland Hall, 3400 N. Charles St, Baltimore, MD 21218, (2)Biophysics, Johns Hopkins University, 221 Maryland Hall, 3400 N. Charles St, Baltimore, MD 21218 |
Virus Engineering for Targeted Gene Delivery
Pin Wang1, Leslie Bailey2 and Kendra Rideout2, (1)Chemical Engineering and Material Science, University of Southern California, 925 Bloom Walk, HED-216, Los Angeles, CA 90089-1211, (2)Chemical Engineering, University of Southern California, 925 Bloom Walk, HED-216, Los Angeles, CA 90089-1211 |
Enhanced Adhesion of Anti-E-Selectin Biodegradable Nanoparticles to Tnf-Α Activated Endothelium in Vitro and in Vivo
Harshad S. Sakhalkar1, Jie Fu2, Sudhir P. Deosarkar1, Xiaoyan Zou1, Mark Christman1, Justin Hanes2, David T. Kurjiaka3 and Douglas J. Goetz1, (1)Ohio University, Department of Chemical Engineering, 172 Stocker Center, Athens, OH 45701, (2)The Johns Hopkins University, Department of Chemical & Biomolecular Engineering, 221 Maryland Hall, 3400 N. Charles Street, Baltimore, MD 21218, (3)Ohio University, Department of Biological Sciences, Athens, OH 45701 |
Stability of High Density Pei/Vegf DNA Nanocomplexes in Physiological Fluids
Yah-el Har-el, Chemical & Biomolecular Engineering, Johns Hopkins University, 220 Maryland Hall, 3400 N. Charles St., Balitmore, MD 21218, John H. Van Zanten, Chemical Engineering, North Carolina State University, Box 7905, Raleigh, NC 27695-7905 and Justin Hanes, Chemical & Biomolecular Engineering, Johns Hopkins University, 221 Maryland Hall, 3400 N. Charles St, Baltimore, MD 21218 |
A Computational Model of Transient Drug/Chemical Diffusion through Human Skin in the Vicinity of a Hair Follicle
Yuri H. Dancik, Chemical and Biological Engineering, University at Buffalo, State University at New York, 511 Furnas Hall, Amherst, NY 14260, Gerald B. Kasting, College of Pharmacy, University of Cincinnati, 407 Health Professions Building, Cincinnati, OH 45267 and Johannes M. Nitsche, Chemical and Biological Engineering, University at Buffalo, State University at New York, 507 Furnas Hall, Amherst, NY 14260 |
Convection Enhanced Drug Infusion into the Soft Brain Tissue
Michalis Xenos, Xuedong Zhou, MahadevaBharath R. Somayaji and Andreas A. Linninger, Chemical Engineering & Bioengineering, University of Illinois at Chicago, 810 S. Clinton St., Chicago, IL 60607 |