Application of Raman and Fbrm Techniques in the Development of Pharmaceutical Crystallization Processes
Lifen Shen, Dimuthu Jayawickrama, Robert Wethman and Victor Hung, Bristol Myers Squibb, New Brunswick, NJ 08902 |
Using Process Analytics to Monitor Drying of an Organic Monohydrate
Jennifer Kuehne1, Charles Van Kirk2, Elisabeth Corbett1 and Ariya Akthakul3, (1)Development Engineering, Bristol-Myers Squibb, 1 Squibb Drive, New Brunswick, NJ 08690, (2)Technical Transfer of Drug Products, Bristol-Myers Squibb, 1 Squibb Drive, New Brunswick, NJ 08690, (3)Engineering Technology, Bristol-Myers Squibb |
Monitoring the Hydrolysis of Acetic Anhydride Using in-Situ Raman Spectroscopy and Novel Multivariate Data Analysis – Band-Target Entropy Minimization (Btem)
Effendi Widjaja, Process Science and Modeling, Institute of Chemical and Engineering Sciences, 1 Pesek Road, Jurong Island, Singapore, 627833, Singapore, Ying Yan Tan, Department of Chemical & Biomolecular Engineering, National University of Singapore, Department of Chemical & Biomolecular Engineering, 4 Engineering Drive 4, Singapore, 117576, Singapore and Marc Garland, Process Science and Modeling, Department of Chemical & Biomolecular Engineering, Institute of Chemical and Engineering Sciences, National University of Singapore, Department of Chemical & Biomolecular Engineering, 4 Engineering Drive 4, Singapore, 117576, Singapore |
A Highly Integrated on-Chip Glycoprotein Processor for Rapid Sialic Acid Content Monitoring
Jinpian Diao1, Lincoln Young2, Peng Zhou2 and Michael L. Shuler1, (1)Cornell University, 120 Olin Hall, Ithaca, NY 14853-5201, (2)Microfluidics Division, Kionix Inc., 36 Thornwood Drive, Ithaca, NY 14850 |
Intermission |
Modeling and Control of Continuous Tumble Mixing of Granular Materials
Carlos Velázquez-Figueroa and Andres F. Valencia-Agudelo, Chemical Engineering, University of Puerto Rico, Mayaguez, PR 00681 |
Continuous Reactive Precipitation in a Y-Mixer
Jason M. Gillian, University of Virginia, 102 Engineers' Way, Charlottesville, VA 22904-4741 and Donald J. Kirwan, University of Virginia, P.O.Box 400741, Charlottesville, VA 22904-4741 |
Implementation of 3 Consecutive Continuous Reactions in the Pilot Plant for Gmp Production of Api
Thomas L. LaPorte1, Mourad Hamedi2, Jeffrey DePue2, Daniel Watson2, Simon Leung2, Daniel Hsieh2, John Shabaker2 and Ehrlic Lo2, (1)Process R&D, Bristol-Myers Squibb Company, One Squibb Drive, New Brunswick, NJ 08903, (2)Bristol-Myers Squibb Company, One Squibb Drive, New Brunswick, NJ 08903 |