Simulation of Particle Movement in a Pan Coating Device Using Discrete Element Modeling and Its Comparison with Video-Imaging Experiments
Preetanshu Pandey1, Yongxin Song1, Ferhan Kayihan2 and Richard Turton1, (1)Department of Chemical Engineering, West Virginia University, 453 Engineering Science Building, PO Box 6102, Morgantown, WV 26506, (2)Integrated Engineering Technologies, 5533 Beverly Ave NE, Tacoma, WA 98422-1402 |
Systematic Modeling of Knowledge in Pharmaceutical Product Development
Ankur Jain1, Chunhua Zhao1, Girish Joglekar1, Leaelaf M. Hailemariam1, Venkat Venkatasubramanian1 and Gintaras Victor Reklaitis2, (1)School of Chemical Engineering, Purdue University, 480 Stadium Mall Drive, West Lafayette, IN 47907, (2)Purdue University, School of Chemical Engineering, 1283 Chemical Engineering Building, West Lafayette, IN 47907 |
A Novel Method for the Quantitative Mapping of the Density Profile of Roller Compacted Ribbons Via near-Infrared Reflectance Spectroscopy
Jeannie Chow1, Nathan C. Pixley2, Craig B. Ikeda1, Celia N. Cruz3 and Justin D. Moser1, (1)Pharmaceutical Development, Merck & Co., Inc., West Point, PA 19486, (2)Pharmaceutical Analysis & Control, Merck & Co., Inc., West Point, PA 19486, (3)Pharmaceutical Materials Lab, Merck & Co., Inc., West Point, PA 19486 |
Prediction of Equilibrium Partitioning of Pharmaceuticals in Octanol-Water and Water-Surfactant Systems
Irina Smirnova1, Matthias Buggert1, Ludmila Mokrushina1, Wolfgang Arlt1 and Reinhard Schomaecker2, (1)Lehrstuhl fuer Thermische Verfahrenstechnik, Friedrich – Alexander Universitaet Erlangen – Nuernberg, Egerlandstr. 3, Erlangen, 91058, Germany, (2)Fachgruppe Technische Chemie, Technische Universitaet Berlin, Str. des 17. Juni 124-128, Berlin, 10623, Germany |
Recovery of Asymmetric Homogeneous Catalysts Using CO2
Jason P. Hallett1, Jie Lu2, Pamela Pollet2, Charles L. Liotta2, Charles A. Eckert2 and Philip G. Jessop3, (1)Chemical and Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive NW, Atlanta, GA 30332-0100, (2)Georgia Institute of Technology, 311 Ferst Dr, Atlanta, GA 30332-0100, (3)Queens University, Chernoff Hall, Kingston, ON K7L, Canada |
Pattern Recognition for Characterization of Pharmaceutical Powders
Alvaro Realpe and Carlos Velázquez, Chemical Engineering, University of Puerto Rico, Miradero, Road 108, Km 3.0, Mayaguez, PR 00680 |
Control of Batch Cooling Crystallization of Glycine
Jia Wei Chew1, Simon N. Black2, Pui Shan Chow1 and Reginald B. H. Tan3, (1)Crystallization and Particle Science, Institute of Chemical and Engineering Sciences, 1, Pesek Road, Jurong Island, Singapore 627833, Singapore, Singapore, (2)Crystallization, AstraZeneca, Silk Road Business Park, Charter Way, Macclesfield, Cheshire, SK10 2NA, Cheshire, United Kingdom, (3)National University of Singapore, 10 Kent Ridge Crescent, Singapore, 119260, Singapore |
Safe Handling of Potent Active Pharmaceutical Ingredients (Apis) in Kilogram Quantities
Christopher N. Nilsen, Sergio Cesco-Cancian, Kirk Sorgi and Xini Zhang, Global Chemical & Pharmaceutical Development, Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 1000 Rt. 202, Room S-213, Raritan, NJ 08869 |
Developing and Implementing High-Throughput Screening of Pharmaceutical Salts and Polymorphs
Raeann Wu, TRD/CHAD/ARD, Novartis Pharmaceuticals Corp, One Health Plaza, East Hanover, NJ 07936, Dimitris Papoutsakis, Novartis Institutes for BioMedical Research, Inc., 250 Massachusetts Avenu, Cambridge, MA 02139 and Peter Karpinski, Novartis Pharmaceuticals Corp, One Health Plaza, East Hanover, NJ 07936 |
Optimization of Monoclonal Antibody Production Using Process Simulation and Scheduling Tools
Demetri P. Petrides, INTELLIGEN, INC., 2326 Morse Avenue, Scotch Plains, NJ 07076 and Charles Siletti, INTELLIGEN, INC., 700 Walton Ave., Mount Laurel, NJ 08054 |
Inverse-Qsar for Pharmaceutical Development Using the Signature Descriptor: Application to Γ-Secretase and Cox-II Inhibitors
Derick C. Weis1, Crystal R. Childers1, Donald P. Visco Jr.2, Shawn Martin3 and Jean-Loup Faulon3, (1)Chemical Engineering, Tennessee Technological University, Cookeville, TN 38505, (2)Tennessee Technological University, Box 5013, Cookeville, TN 38505, (3)Computational Biology Department, Sandia National Laboratories, Albuquerque, NM 87185 |
Application of Raman Spectroscopy in High-Throughput Salt and Polymorph Screening
Lili Feng, Chemical & Analytical Development, Novartis Pharmaceuticals Corporation, One Health Plaza, East Hanover, NJ 07936 and Piotr H. Karpinski, Novartis Pharmaceuticals Corp., One Health Plaza 436/2253, East Hanover, NJ 07963-1080 |
Solving the Inverse-Qsar Problem with Signature Using a Reduced System
Derick C. Weis1, Donald P. Visco Jr.2, Richard LeBorne3, Shawn Martin4 and Jean-Loup Faulon4, (1)Chemical Engineering, Tennessee Technological University, Cookeville, TN 38505, (2)Tennessee Technological University, Box 5013, Cookeville, TN 38505, (3)Mathematics, Tennessee Technological University, Cookeville, TN 38505, (4)Computational Biology Department, Sandia National Laboratories, Albuquerque, NM 87185 |
Use and Implementation of Pat Tools for Particle System Characterization and Reaction Analysis
Benjamin Smith, Particle Systems Characterization - Process Analytical Technology, METTLER TOLEDO, Redmond, WA 98052, Will Kowalchyk, Reaction Analysis, METTLER TOLEDO, Columbia, MD and Terry P. Redman, Particle Systems Characterization, METTLER TOLEDO, Redmond, WA 98052 |
Rapid Response of Large-Scale Influenza Vaccine Production for a Pandemic
Lyle R. Lash III and Henry Y. Wang, Dept. of Chemical Engineering, University of Michigan, 2300 Hayward St., Ann Arbor, MI 48109 |
Adapting Traditional Microemulsion Phase Behavior Techniques to Pharmaceutical Formulation
Ashkan Kamali, Pharmaceutical Research, Merck & Co., Inc., WP78A-31, P.O. Box 4, West Point, PA 19486 and Craig McKelvey, Pharmaceutical Research, Merck & Co., Inc., WP78-302, P.O. Box 4, West Point, PA 19486 |