Session: Advances in API Process Development (2009 Annual Meeting)

Description:

The application of new technologies and approaches in process development laboratories has expedited development timelines, while providing increased process understanding. Authors are encouraged to submit papers discussing novel techniques/approaches aimed at solving difficult process problems and interesting API case studies. Examples could be either from development or production stages.

Sponsor:

Pharmaceuticals

Co-Sponsor(s):

Process Research and Innovation (12a)

Chair:

Partha Mudipalli
Associate Director
Cephalon, Inc.
API Technologies
145 Brandywine Parkway
West Chester, PA 19380
Phone Number: 610-883-5757
Fax Number: 610-883-5751
Email: pmudipal@cephalon.com

Co-Chair:

David Li

Papers:

126f

CFD Prediction of Liquid Homogenization with Variable Viscosity in a Stirred Tank
Thomas Hoermann, Research Center Pharmaceutical Engineering (RCPE); Primoz Ternik, Research Center Pharmaceutical Engineering (RCPE); Johannes G. Khinast, Graz University of Technology

126a

Enabling Novel Drug Delivery Therapies by Nanomilling of APIs: Acceleration of Preclinical and Clinical Pharmaceutical Development Using a Screening Approach
Michael Juhnke, Novartis Pharma AG; Jorg Berghausen, Novartis Pharma AG; Carsten Timpe, Novartis Pharma AG

126b

Decision Support System for Route Selection in Pharmaceutical Process Development
Aruna Manipura, University of Manchester; Paul Sharratt, A*Star. Institute of Chemical and Engineering Sciences; Edward Roberts, University of Manchester; Ian Houson, BRITEST Ltd.; Gary Montague, University of Newcastle upon Tyne.; Elaine Martin, University of Newcastle upon Tyne.; Kiran Fernandes, University of York

126c

Calculation of the Solubility of Pharmaceuticals in Pure and Mixed Solvents
Ioannis G. Economou, National Center for Scientific Research “Demokritos”; Theodora Spyriouni, National Center for Scientific Research “Demokritos”; Xenophon Krokidis, Scienomics SARL

126d

: Development, Optimization, and Scale up of a Human Growth Hormone PEGylation Process
John J. Buckley, Pfizer Global R&D; Gopinath V. Annathur, Pfizer Global R&D; Sa V. Ho, Pfizer Global R&D; Rory Finn, Pfizer Global R&D; Brandi Osborne, Pfizer Global R&D; Denis Boyle, Pfizer Global R&D; Kristen Thomas, Pfizer Global R&D; Althea Micklewright, Pfizer Global R&D

Break

126e

Optimization of An α-Amino Ester Hydrolase for the Synthesis of β-Lactam Antibiotics
Janna Blum, Georgia Institute of Technology; Andreas S. Bommarius, Georgia Institute of Technology

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division

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