This preliminary program is subject to change.

Advances in Biocatalysis and Biosynthesis II


Description:
The focus of this session is to reflect the latest advances in biocatalysis and biosynthesis of small molecules, including fine chemicals, natural products, and biofuels. Suggested topics include, but are not limited to:(1) Discovery and characterization of new biosynthetic pathways; (2)Engineered biosynthesis of new chemical entities; (3) Rational and combinatorial manipulation of biosynthetic pathways; and (4) Optimization of biosynthetic enzymes and pathways. Topics that cover the metabolic engineering of primary metabolites are better suited in the metabolic engineering sections.

Sponsor:
Bioengineering


Chair:
Yi Tang
University of California, Los Angeles
Chemical and BioMolecular Engineering
420 Westwood Plaza
Los Angeles, CA 90096
Phone Number: 310-825-0375
Fax Number: 310-206-4107
Email: yitang@seas.ucla.edu

Co-Chair:
Zhilei Chen

Papers:
Biosynthesis of 3-Hydroxyalkanoic Acids and Lactones in Escherichia Coli
Collin H. Martin, Massachusetts Institute of Technology; Hsien-Chung Tseng, Massachusetts Institute of Technology; Kristala Jones Prather, Massachusetts Institute of Technology
Genetic and Metabolic Perturbation Analysis of the Polyhydroxybutyrate Pathway
Keith EJ Tyo, Massachusetts Institute of Technology; Curt Fischer, Massachusetts Institute of Technology; Gregory Stephanopoulos, Massachusetts Institute of Technology
Cofactor Engineering of a Thermostable Aldo-Keto Reductase Enzyme: Altering Cofactor Specificity and Development of a Novel Directed Evolution Selection Platform
Elliot Campbell, Columbia University; Ian R. Wheeldon, Columbia University; Scott A. Banta, Columbia University
Cross-Catalytic Activity Across Two Subgroups of the Enolase Superfamily
Tracey L. Thaler, Georgia Institute of Technology; Javier Chaparro-Riggers, Georgia Institute of Technology; Thomas A. Rogers, Georgia Institute of Technology; Andreas S. Bommarius, Georgia Institute of Technology
Intermodular Acyltransferase Complementation for Type I Polyketide Synthase
Fong Tian Wong, Stanford University; Alice Y. Chen, Stanford University; Jin Xi, Stanford University; I.I Mathews, Stanford University; Chaitan Khosla, Stanford University
Cross-Talking Between Two Fungal Type I Iterative Polyketide Synthases
Hui Zhou, University of California, at Los Angeles; Yi Tang, University of California, at Los Angeles
Applying the “DNA Assembler” Approach to Study Natural Product Biosynthetic Gene Clusters
Zengyi Shao, University of Illinois at Urbana-Champaign; Yunzi Luo, University of Illinois at Urbana-Champaign; Huimin Zhao, University of Illinois at Urbana-Champaign
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division