Session: Protein Structure, Function, and Stability (2012 Annual Meeting)

Description:

We invite submissions pertaining to protein structure, function, and stability. Studies may include structural or functional analysis, engineering of new proteins, analysis of protein conformational and colloidal stability, mechanisms of protein folding and misfolding, and mechanisms of protein degradation via physical and chemical routes. Reports relevant to other biotechnological products are also welcome.

Sponsor:

Bioengineering

Chair:

Danielle Tullman-Ercek
University of California, Berkeley
Chemical and Biomolecular Engineering
201 Gilman Hall
Berkeley, CA 94720
Phone Number: 510-642-7160
Email: dtercek@calmail.berkeley.edu

Co-chairs:

Hadley D. Sikes
MIT
Chemical Engineering
E19-502C
Cambridge, MA 02139
Phone Number: 617-253-5224
Email: sikes@mit.edu

Joel L. Kaar
Assistant Professor
UC Boulder
Engineering Center
Boulder, CO 80309
Email: joel.kaar@colorado.edu

Michelle A. O'Malley
Assistant Professor
University of California, Santa Barbara
Department of Chemical Engineering
Santa Barbara, CA 93106-5080
Email: momalley@engineering.ucsb.edu

Papers:

308a

Elongation Kinetics of Fibrillar Polyglutamine Aggregates
Regina M. Murphy, University of Wisconsin-Madison; Robert H. Walters, University of Wisconsin-Madison; Kurt Jacobson, University of Wisconsin; Joel Pedersen, University of Wisconsin

308b

Antioxidative Oligomeric Procyanidins Prevent Insulin Fibrillation Via the Formation of Unstructured, off-Pathway Aggregates
Rui Liu, Tianjin University; Rongxin Su, Tianjin University; Mengfan Wang, Tianjin University; Wei Qi, Tianjin University; Zhimin He, Tianjin University

308c

Design and Control of Protein-Protein Interactions to Enhance Stability and Solubility
Marco A. Blanco, University of Delaware; Christopher J. O'Brien, University of Delaware; Joseph Costanzo, University of Virginia; Anne S. Robinson, University of Delaware; Erik J. Fernandez, University of Virginia; Christopher J. Roberts, University of Delaware

308d

Prediction and Accelerated Test of Antibody Aggregation
Jonathan Rubin, Georgia Institute of Technology; Lars Linden, Bayer Pharmaceuticals; Wayne M. Coco, Bayer Healthcare AG; Andreas S. Bommarius, Georgia Institute of Technology; Sven H. Behrens, Georgia Institute of Technology

308e

A Non-Invasive, Quantitative Method to Monitor Misfolding/Aggregation of Protein in Mammalian Cells
Simpson Gregoire, University of Virginia; Joseph Costanzo, University of Virginia; Shaojie Zhang, University of Virginia; Erik J. Fernandez, University of Virginia; Inchan Kwon, University of Virginia

308f

Design of Antibodies Specific for Unfolded Proteins
Ali Reza A. Ladiwala, Rensselaer Polytechnic Institute; Joseph M. Perchiacca, Rensselaer Polytechnic Institute; Moumita Bhattacharya, Rensselaer Polytechnic Institute; Peter M. Tessier, Rensselaer Polytechnic Institute

308g

Interaction of Tau Protein with Model Lipid Membranes Induces Tau Structural Compaction
Emmalee M. Jones, University of New Mexico; Manish Dubey, Los Alamos Neutron Science Center, Los Alamos National Laboratory; Saurabh Singh, Los Alamos Neutron Science Center, Los Alamos National Laboratory; Ann Junghans, Los Alamos Neutron Science Center, Los Alamos National Laboratory; Phillip J. Camp, University of New Mexico; Briana C. Vernon, University of New Mexico; Jacek Biernat, Max Planck Unit for Structural Biology; Eckhard Mandelkow, Max Planck Unit for Structural Biology; Jaroslaw Majewski, Los Alamos National Laboratory; Eva Y. Chi, University of New Mexico

308h

Studies of IRE1alpha Transmembrane Domain Dimerization in Lipid Bilayers
Hyunju Cho, Michigan State University; Ryan LaMarca, Michigan State University; Christina Chan, Michigan State University

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division - See also TI: Comprehensive Quality by Design in Pharmaceutical Development and Manufacture

<< Previous Session | Next Session >>