Session: Quantitative Approaches to Disease Mechanisms & Therapies (2012 Annual Meeting)

Description:

This session highlights applying conventional – e.g., reaction and transport phenomena – and emerging – e.g., dynamical systems and statistical mechanics – concepts from (bio)chemical engineering to aid in understanding disease mechanisms and designing therapies. Submissions that integrate experimental work with simulation and that demonstrate a clear connection between engineering fundamentals and disease pathophysiology are particularly encouraged.

Sponsor:

Engineering Fundamentals in Life Science

Co-Sponsor(s):

Biomedical Applications of Chemical Engineering (T7)

Chair:

David J. Klinke
West Virginia University
Chemical Engineering
Morgantown, WV 26506-6102
Fax Number: 304-293-4139
Email: david.klinke@mail.wvu.edu

Co-Chair:

Keith B. Neeves
Assistant Professor
Colorado School of Mines
Chemical and Biological Engineering
Golden, CO 80401
Email: kneeves@mines.edu

Papers:

309a

Modeling the Diffusive Behavior of 3D Stem Cell Migration
Joshua D. Cohen, MIT; Tyler Vlass, University of Massachussetts, Amherst; Dayong Chen, University of Massachussetts, Amherst; Ryan C. Hayward, University of Massachusetts, Amherst; Shelly R. Peyton, University of Massachussetts, Amherst

309b

Regulatory Role of D'D3 Domain in VWF-A1 Mediated Platelet Thrombus Formation: Application towards Understanding Von Willebrand Disease
Sri R. Madabhushi, State University of New York at Buffalo; Kannayakanahalli Dayananda, State University of New York at Buffalo; Chengwei Shang, State University of New York at Buffalo; Jun Qu, State University of New York at Buffalo; Sriram Neelamegham, State University of New York at Buffalo

309c

Thrombus Growth and Embolism On Tissue Factor-Bearing Collagen Surfaces Under Flow Role of Thrombin with and without Fibrin
Thomas Colace, University of Pennsylvania; Ryan Muthard, Penn State University, University Park; Scott L. Diamond, University of Pennsylvania

309d

A Control Engineering Perspective to Modeling Calcium Regulation and Related Pathologies
Christopher R. Christie, Virginia Polytechnic Institute and State University; Luke E. K. Achenie, Virginia Polytechnic Institute and State University; Babatunde A. Ogunnaike, University of Delaware

309e

A Quantitative Systems Approach to Identify Paracrine Mechanisms That Locally Suppress Immune Response in Melanoma
David J. Klinke, West Virginia University

309f

A Multiscale Model of Acute Insulin Resistance in Critical Illness
Ari Pritchard-Bell, University of Pittsburgh; Gilles Clermont, University of Pittsburgh School of Medicine; Balaji Yegneswaran, University of Pittsburgh; Robert S. Parker, University of Pittsburgh

309g

Systems Biology of Host-Pathogen Interactions
Anu Raghunathan, National Chemical Laboratory; Sookil Shin, Mount Sinai School of Medicine; Simon Daefler, Mt Sinai School of Medicine

309h

Modulating Lipid Fate Controls Lipotoxicity in Palmitate-Treated Hepatic Cells
Alexandra K. Leamy, Vanderbilt University; Jamey D. Young, Vanderbilt University

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division - See also TI: Comprehensive Quality by Design in Pharmaceutical Development and Manufacture

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