Session: Protein Engineering I - Therapeutics (2012 Annual Meeting)

Description:

This session will focus on protein engineering for therapeutic applications with an emphasis on emerging topics and recent successes. Possible areas of interest include, but are not limited to, (1) advances in protein-based therapeutics, (2) proteins for cellular targeting and imaging, and (3) proteins involved in disease pathology.

Sponsor:

Bioengineering

Chair:

Michael C. Jewett
Assistant Professor
Northwestern University
Chemical and Biological Engineering
2145 Sheridan Road
Evanston, IL 60208-3120
Phone Number: (847) 467-5007
Email: m-jewett@northwestern.edu

Co-Chair:

Jin Ryoun Kim
Assistant Professor
Polytechnic Institute of New York University
Chemical and Biological Engineering
6 MetroTech Center
Brooklyn, NY 11201
Phone Number: 718-260-3719
Email: jkim@poly.edu

Papers:

47a

Design of Potent Antibody Inhibitors of Amyloid Fibrillization
Ali Reza A. Ladiwala, Rensselaer Polytechnic Institute; Moumita Bhattacharya, Rensselaer Polytechnic Institute; Joseph M. Perchiacca, Rensselaer Polytechnic Institute; Peter M. Tessier, Rensselaer Polytechnic Institute

47b

Development of Computational Methods to Support De Novo Antibody Design
Robert J. Pantazes, The Pennsylvania State University; Costas D. Maranas, The Pennsylvania State University

47c

Computationally Driven Therapeutic Protein Deimmunization
Regina S. Salvat, Dartmouth; Andrew S. Parker, Dartmouth; Daniel C. Osipovitch, Dartmouth; Chris Bailey-Kellogg, Dartmouth; Karl E. Griswold, Dartmouth

47d

Improved Protein Switches for Cancer-Activated Enzyme Prodrug Therapy
R. Clay Wright, Johns Hopkins University; Arjun Khakhar, Johns Hopkins University; Chapman M. Wright, Johns Hopkins University; James R. Eshleman, Johns Hopkins University School of Medicine; Marc Ostermeier, Johns Hopkins University

47e

Engineered Hepatocyte Growth Factor Mutants: New Tools for Tissue Regeneration and Vascularization
Cassie Liu, Stanford; Douglas S. Jones, Stanford University; Ping-Chuan Tsai, Stanford University; Jennifer R. Cochran, Stanford University

47f

Enzyme Prodrug Therapy Targeted to Breast Tumor Vasculature Using a Recombinant Fusion Protein
John Krais, University of Oklahoma; Vassilios I. Sikavitsas, University of Oklahoma; Carla Kurkjian, University of Oklahoma Health Sciences Center; Roger G. Harrison, University of Oklahoma

47g

Engineering Polymerized Hemoglobins for Use In Transfusion Medicine
Andre Palmer, The Ohio State University

47h

Cell-Based Biosensors for Dynamically Imaging Immune Function in Vivo
Nichole Daringer, Northwestern University; Rachel M. Dudek, Northwestern University; Joshua N. Leonard, Northwestern University

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division - See also TI: Comprehensive Quality by Design in Pharmaceutical Development and Manufacture

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