This preliminary program is subject to change.

Innovations in Drug Delivery Technology II


Description:
Novel drug delivery methods are rapidly growing in number and type. Some of the intended areas of improvement, without excluding others, are sustained release, targeted delivery, enhanced absorption/transport, constant and controllable release through implants, pulmonary systemic delivery, advanced transdermal/transmuscular delivery, sublingual and inguinal delivery, peritoneal delivery, remote actuation, and bioavailability enhancement. While many technologies have been in use for decades, effective use of the right method for the application and drug of interest is the grand challenge. The focus of this session is on innovative design of drug delivery devices and/or the development of associated formulations. Topics of special interest are device development, device performance, intentional formulation development for a specific device, issues surrounding the device-formulation integration, and quantification of the device-formulation-tissue interaction. Papers covering experimental results or modeling of device performance are welcome, but those correlating data with theory are of greatest interest.

Sponsor:
Pharmaceuticals


Chair:
Basar Bilgicer
Assistant Professor
University of Notre Dame
Chemical and Biomolecular Engineering
165 Fitzpatrick Hall
Notre Dame, IN 46556
Fax Number: (574) 631-8366
Email: bbilgicer@nd.edu


Papers:
System Identification and Frequency Response Techniques for the Design of Controlled Release Drug Delivery Systems
Timothy Knab, University of Pittsburgh; Sam N. Rothstein, University of Pittsburgh; Steven R. Little, University of Pittsburgh; Robert S. Parker, University of Pittsburgh
Quantification of Intracellular Distribution of Agents by pH-Responsive Blend Polymer Particles
Xi Zhan, University of Washington; Kenny K. Tran, University of Washington; Hong Shen, University of Washington
Pulsed Release Through Layered Polymers
Swapnil Gandhi, University of Iowa; Eric Nuxoll, University of Iowa
The Impact of Polymer Blends and Solid Dispersion Technologies On Drug Release Rates
Adeyinka Adegoke, University of Rhode Island; David Worthen, University of Rhode Island
A Predictive Model for Coupled Polymer Degradation, Erosion, and Drug Release in PLGA Biodegradable Stent Coatings
Xiaoxiang Zhu, Massachusetts Institute of Technology; Richard D. Braatz, Massachusetts Institute of Technology
Impingement of Printed Droplets Into Porous Medium: Rapid Manufacturing of Personalized Oral Dosages
Marlena Brown, Rutgers University; Paul Takhistov, Cook College, Rutgers, The State University of New Jersey
Rapid Vaccination Via Acetalated Dextran Microparticulate Subunit Vaccine for Protection Against Bacillus Anthracis Challenge
Kevin Schully, Naval Medical Research Center; John Pesce, Naval Medical Research Center; Sadhana Sharma, Ohio State; Margaret Elberson, Naval Medical Research Center; Kevin Peine, Ohio State; Eric M. Bachelder, Ohio State; Andrea Keane-Myers, Naval Medical Research Center; Kristy M. Ainslie, Ohio State
Transdermal Delivery of Biopharmaceuticals Using Dissolving Microneedles Patch
Jeong Woo Lee, Georgia Institute of Technology; Seong-O. Choi, Georgia Institute of Technology; Eric Felner, Emory University; Mark R. Prausnitz, Georgia Institute of Technology