Session: Poster Session: Engineering Fundamentals In Life Science (2012 Annual Meeting)

596a

Engineering Cell-Material Interfaces for Long-Term Expansion of Human Pluripotent Stem Cells
Shyni Varghese, University Of California, San Diego; Yongsung Hwang, University of California, San Diego

596aa

Confocal Fluorescent Microscopy Vs. Direct Enumeration for Quantification of Biofilm Infection Deactivation
Ann O'Toole, University of Iowa; Eric Nuxoll, University of Iowa

596ab

Investigating the Effects of Dynamic External Stimuli On Single Cell Fitness and Gene Expression in E. Coli
Utsav Agrawal, University of Illinois at Urbana-Champaign; Eric Johnson Chavarria, University of Illinois Urbana-Champaign; Arnab Mukherjee, University of Illinois at Urbana-Champaign; Melikhan Tanyeri, University of Illinois at Urbana-Champaign; Charles M. Schroeder, University of Illinois at Urbana-Champaign

596ac

Tunable Synthetic Divergent Promoters
Kang Wu, University of Illinois

596ad

Supercooling: An Alternative Biopreservation Scheme
O. Berk Usta, Massachusetts General Hospital / Harvard Medical School; Basak Uygun, Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Shriners Hospital for Children; Yeonhee Kim, Massachusetts General Hospital / Harvard Medical School; Bote Bruinsma, Massachusetts General Hospital; Tim Berendsen, MGH/Harvard Medical School; Jung Woo Lee, Massachusetts General Hospital/ Harvard Medical School; Korkut Uygun, Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Shriners Hospital for Children; Martin L. Yarmush, Massachusetts General Hospital, Harvard Medical School

596ae

Size-Dependent Cryopreservation of Pluripotent Stem Cell Aggregates
Sebastien Sart, Florida State University; Teng Ma, Florida State University; Yan Li, Florida State University

596af

Role of Transferrin Receptor in Breast Cancers
Suhas Rao, Rensselaer Polytechnic Institute; Patrick T. Underhill, Rensselaer Polytechnic Institute; Pankaj Karande, Rensselaer Polytechnic Institute

596ag

Kinetic Models of Tissue Tropism in Breast Cancer Metastasis
Lauren E. Barney, University of Massachusetts, Amherst; Erinn C. Dandley, University of Massachusetts, Amherst; T. J. Mountziaris, University of Massachusetts; Shelly R. Peyton, University of Massachusetts, Amherst

596ah

A Distinct Phenotypic Signature for Pancreatic Cancer Metastasis
Pei-Hsun Wu, Johns Hopkins University; Jude Phillip, Johns Hopkins University; Wei-Chiang Chen, Johns Hopkins University; Sonal Gupta, Johns Hopkins University School of Medicine; Jeffery T Leek, Johns Hopkins University; Anirban Maitra, Johns Hopkins University School of Medicine; Denis Wirtz, Johns Hopkins University

596ai

Mechanism-Based Pharmacokinetic Model to Predict Endogenous Autoantibody Clearance Levels
Venkat R. Pannala, University of Texas at Dallas; Dilip Challa, University of Texas Southwestern Medical Center; Sally Ward, University of Texas Southwestern Medical Center; Leonidas Bleris, University of Texas at Dallas

596aj

Three Dimensional Tumor Spheroids Through Cell-Instructive Polyamine Based Hydrogels
Thrimoorthy Potta, Arizona State University; Taraka Sai Pavan Grandhi, Arizona State University; Kaushal Rege, Arizona State University

596ak

Doing Cancer Surgery One Cell At a Time
Joseph A. Zasadzinski, University of Minnesota; Dmitri Lapotko, Rice University

596al

Transdifferentiation of Mesenchymal Stem Cells on Micropatterned Polymeric Substrates
Anup Sharma, Iowa State University; Mustafa E. Marti, Iowa State University; Emma Petersen, Iowa State University; Donald S. Sakaguchi, Iowa State University; Surya K. Mallapragada, Iowa State University

596am

Physiologically Based Pharmacokinetic and Pharmacodynamic Approach to Nanoparticle Biodistribution and Tumor Uptake: A Comparison Between Gold Nanoparticles and Spions Nanoparticles
Angel A. Galvis, Universidad de los Andes; Ruben D. Vargas, Universidad de los Andes; Watson L. Vargas, Universidad de los Andes

596an

Selectin-Mediated Adhesion in Shear Flow Using Micropatterned Substrates
Luthur Siu-Lun Cheung, Johns Hopkins University; ZiQiu Tong, Johns Hopkins University; Kathleen J. Stebe, University of Pennsylvania; Konstantinos Konstantopoulos, Johns Hopkins University

596ao

Neutrophil Chemotaxis in Multiple Chemoattractant Gradients Using Microfluidic Platforms
Matthew Byrne, University of Illinois, Urbana Champaign; Yuki Kimura, University of Illinois, Urbana Champaign; Ashish Kapoor, University of Illinois, Urbana Champaign; Fei Wang, University of Illinois, Urbana Champaign; Paul J.A. Kenis, University of Illinois at Urbana Champaign; Christopher V. Rao, University of Illinois, Urbana Champaign

596ap

A Three Compartment Model for Pharmacodynamics and Anomalous Diffusion of Engineered Nanoparticles
Lina Ubaque, Universidad de los Andes; Ruben D. Vargas, Universidad de los Andes; Watson L. Vargas, Universidad de los Andes

596aq

Physiologically Based Three-Compartment Model for Anomalous Diffusion of Gold Nanoparticles with a Pulsed Inlet
Laura M. Hernandez, Universidad de los Andes; Angel A. Galvis, Universidad de los Andes; Ruben D. Vargas, Universidad de los Andes; Watson L. Vargas, Universidad de los Andes

596ar

Interstitial Permeation of Human Blood Clots Formed Under Flow Using Controlled Pressure Gradients in a Microfluidic Model of Bleeding
Ryan W. Muthard, University of Pennsylvania; Scott L. Diamond, University of Pennsylvania

596�as

Calcium-Alginate Mediated Nucleic Acid Delivery in a Microfluidic Device
Jordan F. Betz, University of Maryland; Yi Cheng, University of Maryland; Chen-Yu Tsao, University of Maryland; Hsuan-Chen Wu, University of Maryland; Gregory F. Payne, University of Maryland; William E. Bentley, University of Maryland; Gary W. Rubloff, University of Maryland

596at

Modeling Hematopoiesis: Clinical Applications of Population Balance Models
Jayachandran Devaraj, Purdue University; Doraiswami Ramkrishna, Purdue University

596au

Model-Based Individualized Treatment for Acute Lymphoblastic Leukemia
Jayachandran Devaraj, Purdue University; Ann E. Rundell, Purdue University; Robert E. Hannemann, Purdue University; Doraiswami Ramkrishna, Purdue University

596av

Direct Observation of Von Willebrand Factor Unfolding and Elongation On Collagen During Acute Whole Blood Exposure to Pathological Shear Rates
Thomas Colace, University of Pennsylvania; Scott L. Diamond, University of Pennsylvania

596aw

Interaction Between Coenzyme Q10 and Human Serum Albumin: Spectroscopic Approach
Yinhe Sun, Tianjin University; Xin Peng, Tianjin University; Wei Qi, Tianjin University; Mengfan Wang, Tianjin University; Rongxin Su, Tianjin University; Zhimin He, Tianjin University

596ax

PEI/Nucleic Acid Polyplex Preparation for the Optimized Size, Gene Transfection, and Cytotoxicity: Implications in Nonviral Gene Delivery
Soo Kyung Cho, University of California, Irvine; Chris Dang, University of California, Irvine; Jones Tsai, University of California, Irvine; Young Jik Kwon, University of California, Irvine

596ay

A Multiplexed Microfluidic Platform for Antibiotic Susceptibility Screening
Ritika Mohan, University of Illinois at Urbana-Champaign; Arnab Mukherjee, University of Illinois at Urbana-Champaign; Jaebum Lee, University of Illinois at Urbana-Champaign; Emre Sevgen, University of Illinois at Urbana-Champaign; Charles M. Schroeder, University of Illinois at Urbana-Champaign; Paul J. A. Kenis, University of Illinois at Urbana-Champaign

596az

Characterizing Fluid Dynamics of Impinging Jet Mixing with Ultrasonic Excitation Using Particle Image Velocimetry
David M. Rophael, The Cooper Union for the Advancement of Science and Art; John C. Consiglio, The Cooper Union for the Advancement of Science and Art; Christian Beck, New Jersey Institute of Technology; David Wootton, The Cooper Union for the Advancement of Science and Art; Rajesh N. Dave, New Jersey Institute of Technology

596b

Controlled Rupture of Drug-Encapsulated Ultrasound Contrast Agents
Yoonjee Park, Boston University; Tuan Pham, Boston University; Carl Beigie, Boston University; Robin Cleveland, University of Oxford; Jon O. Nagy, NanoValent Pharmaceuticals; Joyce Y. Wong, Boston University

596ba

Lead Identification, Optimization, and Characterization of Novel Cancer Treatment Strategies Using Repositioned Drugs
David J. Taylor, Arizona State University; Jeongyun Kim, Texas A&M University; Arul Jayaraman, Texas A&M University; Kaushal Rege, Arizona State University

596bb

Using Vibrational Spectroscopy to Evaluate Solid Disperision Stability
Ryanne N. Palermo, Duquesne University; Carl A. Anderson, Duquesne University; James K. Drennen III, Duquesne University

596bc

Effects of Oscillatory Convective Flow On Chemical Signal Propagation in Epithelia
Michal Pribyl, Institute of Chemical Technology, Prague; Marek Nebyla, Institute of Chemical Technology, Prague

596c

Expansion of Functional Human Amniotic Fluid Stem Cells in Serum Free Medium
Meimei Liu, The Ohio State University; Ning Liu, Irvine Scientific; Shang-Tian Yang, Ohio State University

596d

Oxygen Sensing and Control of Engineered Tissue
Seema M. Ehsan, University of California, Irvine; Steven C. George, University of California, Irvine

596e

Cell Communication in Three Dimensional Microenvironments
Matthew Byrne, University of Illinois, Urbana Champaign; Lisa Trump, University of Illinois at Urbana-Champaign; Amit V. Desai, University of Illinois at Urbana-Champaign; Lauretta A. Rund, University of Illinois Urbana-Champaign; Lawrence B. Schook, University of Illinois Urbana-Champaign; Paul J. A. Kenis, University of Illinois, Urbana Champaign

596f

Single-Particle Assay for Characterizing the Binding Kinetics of X31 Influenza Virus and the Efficacy of Antiviral Compounds
Donald Lee, Cornell; Susan Daniel, Cornell University

596h

Effects of Histone Tail Modifications On Chromosome Structure and Activity
Nate Nurse, Purdue University; Chongli Yuan, Purdue University

596i

Design, Synthesis and Characterization of Protein-Based Surfactants As Functional Drug Stabilizers
Rachael Barton, Lehigh University; Kevin Sledziewski, Particle Sciences, Inc.; Philo Morse, Particle Sciences, Inc.; Robert Lee, Particle Sciences, Inc.; Bryan W. Berger, Lehigh University

596j

Effect of Fibril Alignment On Macromolecule Diffusion in Fibrin Gels
Armen H. Mekhdjian, Stanford University; Arjun S. Adhikari, Stanford University; Alexander R. Dunn, Stanford University

596k

Biomedical Potentials of Bacterial Fibrinolytic Enzymes
Sudhir Rai, NICHD, NIH

596l

Encapsulation of Adjuvant in Acetalated Dextran Microparticles for Production of Subunit Vaccines Using an Electrospray Method
Anthony Duong, The Ohio State University; Sadhana Sharma, The Ohio State University; Eric M. Bachelder, The Ohio State University; Barbara E. Wyslouzil, The Ohio State University; Kristy M. Ainslie, The Ohio State University

596n

Scaffold Fabrication From Cadaver Goat Lung Tissue and Its Biocompatibility Study for Tissue Engineering Applications
Sweta Gupta, Indian Institute of Technology Roorkee; Amit K. Dinda, All India Institute Of Medical Sciences; Narayan C. Mishra, Indian Institute of Technology Roorkee, Roorkee,India

596o

Effect of Poly(ethylene glycol) Spacers On the Vascular Targeting of Particles to Endothelium in Blood
Peter Onyskiw, University of Michigan; Omolola Eniola-Adefeso, University of Michigan

596p

Food-Associated Stimuli Impact On Particle Penetration Through Gastrointestinal Mucus Barrier
Hasan M. Yildiz, Northeastern University; Rebecca L. Carrier, Northeastern University

596r

Delivery Systems for Controlled and Sustained Release of Malarial Inhibitors
Christina Yacoob, University of Washington; Kayode K. Ojo, University of Washington; Steven M. Johnson, University of Washington; Dustin J. Maly, University of Washington; Wesley C. Van Voorhis, University of Washington; Hong Shen, University of Washington

596s

Investigation of Clock Protein Interactions by Surface Plasmon Resonance
Burcu Kepsutlu, Koc University; Hande Asimgil, Koc University; Bilal Cakir, Washington State University; Dogan Gidon, Koc University; Gozde Sultan Demirer, Koc University; Riza Kizilel, Koc University; I. Halil Kavakli, Koc University; Seda Kizilel, Koc University

596t

Exploring Beta-Amyloid's Alteration of Signaling Cascades Associated with Learning and Memory of Neuron-Like Cells and the Subsequent Implication in the Mechanism of Alzheimer's Disease
Arundhathi K. Venkatasubramaniam, University of Maryland Baltimore County; Theresa Good, University of Maryland Baltimore County

596u

Developing a Quantitative Method to Investigate Receptor Oligomerization: Applications to Receptor for Advanced Glycation Endproducts (RAGE)
Pin-Chuan Su, Lehigh University; Bryan W. Berger, Lehigh University

596v

Nuclear Mechanics in Crawling Cells
Jun Wu, University of Florida; TJ Chancellor, University of Florida; Nandini Shekhar, University of Florida; Agnes Mendonca, University of Florida; Kyle Roux, Sanford Children's Health Research Center; Richard Dickinson, University of Florida; Tanmay Lele, University of Florida

596w

Single-Cell Characterization of CD19-Specific CAR⁺ T Cells for Immunotherapy
Ivan Liadi, The University of Houston; Jason Roszik, The University of Texas MD Anderson Cancer Center; Amin Merouane, The University of Houston; Gabrielle Romain, The University of Houston; Badri Roysam, The University of Houston; Laurence Cooper, The University of Texas MD Anderson Cancer Center; Navin Varadarajan, The University of Houston

596x

13C Isotopic Tracers to Elucidate Metabolic Dependences of Renal Cell Carcinoma Cells
Paulo A. Gameiro, Massachusetts Institute of Technology; Juanjuan Yang, Massachusetts General Hospital; Othon Iliopoulos, Massachusetts General Hospital; Gregory Stephanopoulos, Massachusetts Institute of Technology

596y

Vessel Wall Transport: Can Increasing the Concentration of the Membrane Protein Aquaporin-1 Slow Down Pre-Lesion Atherosclerosis?
Shripad D. Joshi, City College and Graduate Center of City University of New York; Kung-Ming Jan, College of Physician and Surgeons, Columbia University; David S. Rumschitzki, The City College of The City University of New York

596z

A Long Wavelength Fluorescent Sphingosine As a Tool to Visualize Sphingolipid Transport and Location in Living Cells
Raehyun Kim, University of Illinois, Urbana-Champaign; Kaiyan Lou, University of Illinois at Urbana-Champaign; Mary L. Kraft, University of Illinois at Urbana-Champaign