260 Model Based Integrated Design of Pharmaceutical Drug Substance and Drug Product and Processes I

Tuesday, November 5, 2013: 8:30 AM
Plaza A (Hilton)
Description:
This session seeks contributions where the design of the pharmaceutical product or process has been aided with a mathematical model. The session is open to contributions from the drug substance and drug product side of the business. Authors are encouraged to highlight the downstream considerations in the design.

Sponsor:
Pharmaceutical Discovery, Development and Manufacturing Forum

Chair:
Jeremy Merritt
Email: MERRITT_JEREMY_MILES@LILLY.COM

Co-Chair:
Salvador García-Muñoz
Email: sal.garcia@lilly.com


8:30 AM
(260a) Applications of Modeling and Simulating Moisture Profiles During Fluid Bed Granulation Process Development
Steve Mehrman, John Cunningham, Eric Sanchez, Mauricio Futran, Terry Murphy, James Weber, Adam Fermier, Ray Boucher and Andrew Skalkin

8:55 AM
(260b) Understanding Micro Environmental Thermodynamics of Tablet Coating Process Using Data Logger – Case Studies
Ganeshkumar A. Subramanian, Preetanshu Pandey, Jiangning Ji, Shruti Gour and Brian Zacour

9:20 AM
(260c) An Integrated Model for the Thermodynamics of the Film Coating Operation the Mixing Phenomena in the Drum and the Distribution of Properties in the Coated Tablet
Salvador García-Muñoz, Alejandro Cano, Jianfeng Li, Daniel O. Blackwood and Alfred Berchielli

9:45 AM
(260d) Experimental and Theoretical Study of Tablet Flow in a Lab Scale Pan Coater
Gregor Toschkoff, Peter Böhling, David Johnson, Jennifer Sun, Alan R. Silverman, Georg Scharrer, Johannes G. Khinast and Pavol Rajniak

10:10 AM
(260e) Use of Mechanistic Modeling to Understand Tablet Die Filling
RJ Byron Smith, Atul Dubey, Fernando J. Muzzio and Damodaran Vedapuri

10:35 AM
(260f) Application of Fracture Mechanics Model for the Characterization of Bilayer Tablets
Niranjan Kottala, Admassu Abebe, Omar L. Sprockel, Ilgaz Akseli, Faranak Nikfar and Alberto Cuitino
See more of this Group/Topical: Pharmaceutical Discovery, Development and Manufacturing Forum
<< Previous Session | Next Session >>