568 Process Scale-up Techniques


Description:
A mixture of Art & Science, process scale-up is a complex and vital task in new process development involving bench-scale and pilot plant activities. This session brings together papers in an effort to teach best practices in process scale-up. The session will include papers that describe work using on-line analytics and modeling.

Sponsor:
Pilot Plants
Co-Sponsor(s):
Process Development Division (12)


Chair:
Vaibhav Kelkar
Staff Scientist
SABIC Americas
Sugar Land, TX
Phone Number: 2812433772
Email: vkelkar@sabic.com

Co-Chair:
Shweta Karwa
Shell

Email: Shweta.Karwa@shell.com


Papers:
568a
Liquid-Liquid Extraction: A Simplified View of a Complex Process
Jacob H. Arredondo, Rice University; Timothy Threatt, Rice University; Jonathan H. Worstell, Worstell and Worstell, Consultants
568b
The inside Story of an Extractive Distillation Column: Process Modelling Based Scale-up with Plant Data in a Debottlenecking Case Study
Sekhar Babu Mamilla, SABIC Limburg B.V.; Antonio Matarredona, SABIC Limburg B.V.
568c
Applying CFD Towards Defining Crystallisation Scale up Strategy
Justine Forkin, APC Ltd; Justin O'Sullivan, APC Ltd
568d
Lab Scale Experimental Workflow to De-Risk Production Equipment Change for Filtration and Drying of Active Pharmaceutical Ingredients
Claire MacLeod, AstraZeneca; Caroline Ainsworth, AstraZeneca; Lucie Miller-Potucka, AstraZeneca; Anna Parsons, AstraZeneca; Alexandra Parker, AstraZeneca; David Wilson, AstraZeneca
191bo
Development of  a Pegylated Protein for Large Scale Manufacturing
Nikhil Peer, Genentech, Inc.; Amy Lim, Genentech, Inc.; Elaine Shepard, Genentech Inc.
568f
Multiscale Approach to the Design of a Trickle Bed Reactor
Vaibhav Kelkar, SABIC Americas; Sanjeev M. Rao, SABIC Americas; Debashis Chakraborty, SABIC; Jorge Jimenez, SABIC Americas, Inc.
Abstract Submissions Closed
See more of this Group/Topical: Process Development Division
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