569 Protein Engineering II: Combinatorial Techniques


Description:
The focus of this session will be on the evaluation and implementation of new combinatorial techniques for protein engineering. This includes combinatorial library design, combinatorial library synthesis, high throughput screening/selection techniques, and other novel protein engineering methods. Emphasis will be placed on new techniques or the implementation of existing techniques to address new challenges. Theoretical and experimental work, or a combination thereof, will be considered.

Sponsor:
Bioengineering


Chair:
Amy J. Karlsson
Assistant Professor
University of Maryland
Chemical and Biomolecular Engineering
1223C Chemical and Nuclear Engineering
College Park, MD
20742
Email: ajkarl@umd.edu

Co-Chair:
Zengyi Shao
Assistant Professor
Iowa State University
Department of Chemical and Biological Engineering
4140 Biorenewable Research Laboratory
Ames, IA
50011
Email: zyshao@iastate.edu


Papers:
569a
Mutual Information to Inform Protein Library Design
George C. Markou, University of Minnesota; Casim A. Sarkar, University of Minnesota
569b
Blueprints for Diversifying Small Protein Scaffolds in the Context of Multiple Secondary Structures
Daniel R. Woldring, University of Minnesota; Max A. Kruziki, University of Minnesota; Benjamin J. Hackel, University of Minnesota
569c
A Structure-Based High-Throughput Screening Method for Multi-Step Enzymatic Reactions Using Optically-Guided Mass Spectrometry Profiling of Microbial Colonies
Tong Si, University of Illinois at Urbana-Champaign; Bin Li, University of Illinois at Urbana-Champaign; Troy J. Comi, University of Illinois at Urbana-Champaign; Huimin Zhao, University of Illinois at Urbana-Champaign; Jonathan V. Sweedler, University of Illinois at Urbana-Champaign
569d
Yeast Surface Display of Full Length Human Tau for Combinatorial Antibody Profiling
Shiyao Wang, University of Connecticut; Yongku Cho, University of Connecticut
569e
Saturation Mutagenesis Panning Libraries Enable Activity and Specificity Modulation of Microcin J25
Seth Ritter, University of Minnesota; Mike Yang, University of Minnesota; Yiannis N. Kaznessis, University of Minnesota; Benjamin J. Hackel, University of Minnesota
569f
Accessing the Location-Dependent Effects of Unnatural Amino Acids on Protein Expression and Activity with Cell-Free Protein Synthesis-Facilitated Rapid Screening
Bradley C. Bundy, Brigham Young University; Song-Min Schinn, Brigham Young University; William Bradley, Brigham Young University; Ashtyn Groesbeck, Brigham Young University; Jeffrey C. Wu, Brigham Young University; Andrew Broadbent, Brigham Young University
569g
RNA-Programmed DNA Methylation
Marc Ostermeier, Johns Hopkins University
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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